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Broken sleep predicts hardened blood vessels.
Vallat, Raphael; Shah, Vyoma D; Redline, Susan; Attia, Peter; Walker, Matthew P.
Afiliação
  • Vallat R; Center for Human Sleep Science, Department of Psychology, University of California, Berkeley, California, United States of America.
  • Shah VD; Center for Human Sleep Science, Department of Psychology, University of California, Berkeley, California, United States of America.
  • Redline S; Department of Medicine, Brigham and Women's Hospital and Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, Massachusetts, United States of America.
  • Attia P; Attia Medical, PC, San Diego and New York City, United States of America.
  • Walker MP; Center for Human Sleep Science, Department of Psychology, University of California, Berkeley, California, United States of America.
PLoS Biol ; 18(6): e3000726, 2020 06.
Article em En | MEDLINE | ID: mdl-32497046
ABSTRACT
Why does poor-quality sleep lead to atherosclerosis? In a diverse sample of over 1,600 individuals, we describe a pathway wherein sleep fragmentation raises inflammatory-related white blood cell counts (neutrophils and monocytes), thereby increasing atherosclerosis severity, even when other common risk factors have been accounted for. Improving sleep quality may thus represent one preventive strategy for lowering inflammatory status and thus atherosclerosis risk, reinforcing public health policies focused on sleep health.
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Privação do Sono / Vasos Sanguíneos Tipo de estudo: Prognostic_studies Limite: Aged / Female / Humans / Male / Middle aged Idioma: En Revista: PLoS Biol Ano de publicação: 2020 Tipo de documento: Article
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Privação do Sono / Vasos Sanguíneos Tipo de estudo: Prognostic_studies Limite: Aged / Female / Humans / Male / Middle aged Idioma: En Revista: PLoS Biol Ano de publicação: 2020 Tipo de documento: Article