Coronavirus disease 2019 in an orthotopic liver transplant recipient living with human immunodeficiency virus.
Transpl Infect Dis
; 22(5): e13351, 2020 Oct.
Article
em En
| MEDLINE
| ID: mdl-32500666
ABSTRACT
Coronavirus disease 2019 (COVID-19), mediated by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), can manifest with flu-like illness and severe pneumonia with acute respiratory distress syndrome (ARDS). Immunocompromised patients merit particular attention as altered host immunity may influence both disease severity and duration of viral shedding as is described with several other ribonucleic acid respiratory viruses. Yet immunocompromised status alone, in the absence of other comorbidities, may not necessarily predict severe illness presentations and poorer clinical outcomes as indicated by recent reports of COVID-19-infected solid organ transplant recipients and people living with human immunodeficiency virus (HIV). Such patients may even be spared the robust inflammatory response that precipitates ARDS associated with COVID-19, complicating the management of iatrogenic immunosuppression in this setting. We present a case of an orthotopic liver transplant recipient with well-controlled HIV who successfully recovered from a mild, flu-like illness attributed to SARS-CoV-2.
Palavras-chave
Texto completo:
1
Coleções:
01-internacional
Contexto em Saúde:
1_ASSA2030
/
2_ODS3
/
4_TD
Base de dados:
MEDLINE
Assunto principal:
Infecções por HIV
/
Transplante de Fígado
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Fármacos Anti-HIV
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SARS-CoV-2
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COVID-19
Tipo de estudo:
Etiology_studies
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Prognostic_studies
Limite:
Adult
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Humans
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Male
Idioma:
En
Revista:
Transpl Infect Dis
Ano de publicação:
2020
Tipo de documento:
Article