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Inhibition of decidual IGF-1 signaling in response to hypoxia and leucine deprivation is mediated by mTOR and AAR pathways and increased IGFBP-1 phosphorylation.
Abu Shehab, Majida; Biggar, Kyle; Kakadia, Jenica H; Dhruv, Manthan; Jain, Bhawani; Nandi, Pinki; Nygard, Karen; Jansson, Thomas; Gupta, Madhulika B.
Afiliação
  • Abu Shehab M; Department of Pediatrics, University of Western Ontario, London, ON, Canada.
  • Biggar K; Department of Biology and Institute of Biochemistry, Carleton University, Ottawa, ON, Canada. Electronic address: kyle_biggar@carleton.ca.
  • Kakadia JH; Department of Biochemistry, University of Western Ontario, London, ON, Canada.
  • Dhruv M; Department of Biochemistry, University of Western Ontario, London, ON, Canada.
  • Jain B; Department of Biochemistry, University of Western Ontario, London, ON, Canada.
  • Nandi P; Department of Pediatrics, University of Western Ontario, London, ON, Canada.
  • Nygard K; Biotron Integrated Microscopy Facility, University of Western Ontario, London, ON, Canada.
  • Jansson T; Department of Obstetrics and Gynecology, Division of Reproductive Sciences, University of Colorado Anschutz Medical Campus, Aurora, CO, USA.
  • Gupta MB; Department of Pediatrics, University of Western Ontario, London, ON, Canada; Department of Biochemistry, University of Western Ontario, London, ON, Canada; Children's Health Research Institute, London, ON, Canada. Electronic address: mbgupta@uwo.ca.
Mol Cell Endocrinol ; 512: 110865, 2020 07 15.
Article em En | MEDLINE | ID: mdl-32502935
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Hipóxia Celular / Decídua / Leucina Limite: Female / Humans Idioma: En Revista: Mol Cell Endocrinol Ano de publicação: 2020 Tipo de documento: Article
Texto completo
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Hipóxia Celular / Decídua / Leucina Limite: Female / Humans Idioma: En Revista: Mol Cell Endocrinol Ano de publicação: 2020 Tipo de documento: Article