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Manufacturing of hybrid drug delivery systems by utilizing the fused filament fabrication (FFF) technology.
Eleftheriadis, Georgios K; Katsiotis, Christos S; Genina, Natalja; Boetker, Johan; Rantanen, Jukka; Fatouros, Dimitrios G.
Afiliação
  • Eleftheriadis GK; Department of Pharmacy, Aristotle University of Thessaloniki , Thessaloniki, Greece.
  • Katsiotis CS; Department of Pharmacy, Aristotle University of Thessaloniki , Thessaloniki, Greece.
  • Genina N; Department of Pharmacy, University of Copenhagen , Copenhagen, Denmark.
  • Boetker J; Department of Pharmacy, University of Copenhagen , Copenhagen, Denmark.
  • Rantanen J; Department of Pharmacy, University of Copenhagen , Copenhagen, Denmark.
  • Fatouros DG; Department of Pharmacy, Aristotle University of Thessaloniki , Thessaloniki, Greece.
Expert Opin Drug Deliv ; 17(8): 1063-1068, 2020 08.
Article em En | MEDLINE | ID: mdl-32511025
The potential of fused filament fabrication (FFF) for the administration of active pharmaceutical compounds is a recent approach to develop complex and custom-made drug delivery systems (DDSs). However, the FFF technology is characterized by certain limitations, which are associated with the nature of the process, i.e., the required mechanical properties of the feedstock, as well as the thermal stability of the incorporated polymers, excipients and active compounds. Thus, hybrid DDSs have been recently introduced, to overcome these boundaries. The concept of these systems is defined by the effective coupling of FFF with conventional manufacturing technologies, as a novel pathway to expand the available pool of raw materials and pharmaceutical applications of FFF.
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Preparações Farmacêuticas / Sistemas de Liberação de Medicamentos Idioma: En Revista: Expert Opin Drug Deliv Ano de publicação: 2020 Tipo de documento: Article

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Preparações Farmacêuticas / Sistemas de Liberação de Medicamentos Idioma: En Revista: Expert Opin Drug Deliv Ano de publicação: 2020 Tipo de documento: Article