Rapid Diagnosis of a Family Cluster of Pertussis Starting from a Child: a Case Report.
Clin Lab
; 66(6)2020 Jun 01.
Article
em En
| MEDLINE
| ID: mdl-32538045
ABSTRACT
BACKGROUND:
Pertussis, caused by Bordetella pertussis (B. pertussis), is a highly transmissible, acute respiratory disease that occurs in many countries. Diagnosis of pertussis continues to be a challenge using traditional tests due to their turn-around time and sensitivity. Herein, we rapidly and accurately screened a family cluster of pertussis from a child and her mother.METHODS:
We used an automated nested multiplex PCR system which included B. pertussis, influenza A virus, and 19 other respiratory pathogens.RESULTS:
We detected B. pertussis, influenza A virus H1-2009 (FluA-2009), adenovirus, and respiratory syncytial virus (RSV) in the child, and the mother of the child was positive for B. pertussis and FluA-2009.CONCLUSIONS:
Active and timely screening for pertussis of adult family members should be considered. The detection of multiple respiratory pathogens may guide effective antibiotic therapies. This could be a novel test for the prevention of pertussis.
Texto completo:
1
Coleções:
01-internacional
Contexto em Saúde:
2_ODS3
Base de dados:
MEDLINE
Assunto principal:
Antivirais
/
Vírus da Influenza A
/
Vírus Sinciciais Respiratórios
/
Bordetella pertussis
/
Adenoviridae
/
Coqueluche
/
Reação em Cadeia da Polimerase Multiplex
/
Antibacterianos
Tipo de estudo:
Diagnostic_studies
Limite:
Adult
/
Female
/
Humans
/
Infant
Idioma:
En
Revista:
Clin Lab
Ano de publicação:
2020
Tipo de documento:
Article