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The secondary bile acids, ursodeoxycholic acid and lithocholic acid, protect against intestinal inflammation by inhibition of epithelial apoptosis.
Lajczak-McGinley, Natalia K; Porru, Emanule; Fallon, Ciara M; Smyth, Jessica; Curley, Caitriona; McCarron, Paul A; Tambuwala, Murtaza M; Roda, Aldo; Keely, Stephen J.
Afiliação
  • Lajczak-McGinley NK; Department of Molecular Medicine, Royal College of Surgeons in Ireland, Beaumont Hospital, Dublin 9, Ireland.
  • Porru E; Department of Chemistry, University of Bologna, Bologna, Italy.
  • Fallon CM; Department of Molecular Medicine, Royal College of Surgeons in Ireland, Beaumont Hospital, Dublin 9, Ireland.
  • Smyth J; Department of Molecular Medicine, Royal College of Surgeons in Ireland, Beaumont Hospital, Dublin 9, Ireland.
  • Curley C; Department of Molecular Medicine, Royal College of Surgeons in Ireland, Beaumont Hospital, Dublin 9, Ireland.
  • McCarron PA; School of Pharmacy and Pharmaceutical Sciences, Ulster University, Coleraine, Northern Ireland.
  • Tambuwala MM; School of Pharmacy and Pharmaceutical Sciences, Ulster University, Coleraine, Northern Ireland.
  • Roda A; Department of Chemistry, University of Bologna, Bologna, Italy.
  • Keely SJ; INBB, National Institute of Bio structures and Biosystems, Rome, Italy.
Physiol Rep ; 8(12): e14456, 2020 06.
Article em En | MEDLINE | ID: mdl-32562381
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Texto completo: 1 Coleções: 01-internacional Contexto em Saúde: 6_ODS3_enfermedades_notrasmisibles Base de dados: MEDLINE Assunto principal: Ácido Ursodesoxicólico / Doenças Inflamatórias Intestinais / Substâncias Protetoras / Mucosa Intestinal / Ácido Litocólico Tipo de estudo: Prognostic_studies Limite: Animals Idioma: En Revista: Physiol Rep Ano de publicação: 2020 Tipo de documento: Article
Texto completo
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Texto completo: 1 Coleções: 01-internacional Contexto em Saúde: 6_ODS3_enfermedades_notrasmisibles Base de dados: MEDLINE Assunto principal: Ácido Ursodesoxicólico / Doenças Inflamatórias Intestinais / Substâncias Protetoras / Mucosa Intestinal / Ácido Litocólico Tipo de estudo: Prognostic_studies Limite: Animals Idioma: En Revista: Physiol Rep Ano de publicação: 2020 Tipo de documento: Article