Influenza virus glycoprotein-reactive human monoclonal antibodies.

Li, Yanbai; Wang, Lili; Si, Helong; Yu, Zhengsen; Tian, Shijun; Xiang, Rong; Deng, Xiaoqian; Liang, Ruiying; Jiang, Shibo; Yu, Fei

Li, Yanbai; Wang, Lili; Si, Helong; Yu, Zhengsen; Tian, Shijun; Xiang, Rong; Deng, Xiaoqian; Liang, Ruiying; Jiang, Shibo; Yu, Fei.

Afiliação

Li Y; College of Life Sciences, Hebei Agricultural University, Baoding, China.
Wang L; Research Center of Chinese Jujube, Hebei Agricultural University, Baoding, China.
Si H; College of Life Sciences, Hebei Agricultural University, Baoding, China.
Yu Z; College of Life Sciences, Hebei Agricultural University, Baoding, China.
Tian S; College of Life Sciences, Hebei Agricultural University, Baoding, China.
Xiang R; College of Life Sciences, Hebei Agricultural University, Baoding, China.
Deng X; College of Life Sciences, Hebei Agricultural University, Baoding, China.
Liang R; College of Life Sciences, Hebei Agricultural University, Baoding, China.
Jiang S; Key Laboratory of Medical Molecular Virology (MOE/NHC/CAMS), School of Basic Medical Sciences, Fudan University, Shanghai, China. Electronic address: shibojiang@fudan.edu.cn.
Yu F; College of Life Sciences, Hebei Agricultural University, Baoding, China. Electronic address: shmyf@hebau.edu.cn.

Microbes Infect ; 22(6-7): 263-271, 2020.

Article em En | MEDLINE | ID: mdl-32569735

RESUMO

Influenza continues to be a significant public health challenge. Two glycoproteins on the surface of influenza virus, hemagglutinin and neuraminidase, play a prominent role in the process of influenza virus infection and release. Monoclonal antibodies targeting glycoproteins can effectively prevent the spread of the virus. In this review, we summarized currently reported human monoclonal antibodies targeting glycoproteins of influenza A and B viruses.

Assuntos

Anticorpos Monoclonais/imunologia; Glicoproteínas de Hemaglutininação de Vírus da Influenza/imunologia; Vírus da Influenza A/imunologia; Vírus da Influenza B/imunologia; Neuraminidase/imunologia; Animais; Anticorpos Monoclonais/uso terapêutico; Anticorpos Neutralizantes/imunologia; Anticorpos Neutralizantes/uso terapêutico; Epitopos; Glicoproteínas de Hemaglutininação de Vírus da Influenza/química; Glicoproteínas de Hemaglutininação de Vírus da Influenza/metabolismo; Humanos; Neuraminidase/química; Neuraminidase/metabolismo; Infecções por Orthomyxoviridae/terapia; Infecções por Orthomyxoviridae/virologia

Palavras-chave

Glycoproteins; Hemagglutinin; Influenza A virus; Influenza B virus; Monoclonal antibodies; Neuraminidase

Texto completo

Imprimir

XML

PubMed Links

Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Vírus da Influenza A / Vírus da Influenza B / Glicoproteínas de Hemaglutininação de Vírus da Influenza / Anticorpos Monoclonais / Neuraminidase Limite: Animals / Humans Idioma: En Revista: Microbes Infect Ano de publicação: 2020 Tipo de documento: Article

Texto completo

Imprimir

XML

PubMed Links

Buscar no Google