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Antimicrobial susceptibility surveillance of bacterial isolates recovered in Japan from odontogenic infections in 2013.
Kaneko, Akihiro; Matsumoto, Tetsuya; Iwabuchi, Hiroshi; Sato, Junko; Wakamura, Tomotaro; Kiyota, Hiroshi; Tateda, Kazuhiro; Hanaki, Hideaki; Sakakibara, Noriyuki; Mizuno, Takayuki; Miyajima, Hisashi; Naito, Hiroyuki; Takagi, Ritsuo; Kodama, Yasumitsu; Yamaguchi, Akira; Akasiba, Ryo; Yamane, Nobuo; Jinbu, Yoshinori; Kusama, Mikio; Miyagi, Norito; Kato, Reiko; Nakatogawa, Noriko; Izawa, Kazumi; Tanzawa, Hideki; Kozu, Yoshinao; Watanabe, Hideki; Matsumoto, Koichi; Shibahara, Takahiko; Busujima, Yasunobu; Takato, Tsuyoshi; Sakamoto, Haruo; Watanabe, Daisuke; Kubota, Hiroyuki; Sasaki, Jiro; Uematsu, Masataka; Sasaki, Masashi; Kaetsu, Atsuo; Terasawa, Fumitaka; Yura, Yoshiaki; Iwai, Soichi; Morita, Shosuke; Matsumoto, Kazuhiro; Oonishi, Tetsuo; Komori, Takahide; Furudoi, Shungo; Fujibayashi, Junko; Urade, Masahiro; Kishimoto, Hiromitsu; Yoshii, Takashi; Morihana, Takefumi.
Afiliação
  • Kaneko A; The Surveillance Committee of Japanese Society of Chemotherapy (JSC), The Japanese Association for Infectious Diseases (JAID) and The Japanese Society for Clinical Microbiology (JSCM), Tokyo, Japan; Tokai University Hospital, Kanagawa, Japan. Electronic address: neko-1@ja2.so-net.ne.jp.
  • Matsumoto T; The Surveillance Committee of Japanese Society of Chemotherapy (JSC), The Japanese Association for Infectious Diseases (JAID) and The Japanese Society for Clinical Microbiology (JSCM), Tokyo, Japan.
  • Iwabuchi H; The Surveillance Committee of Japanese Society of Chemotherapy (JSC), The Japanese Association for Infectious Diseases (JAID) and The Japanese Society for Clinical Microbiology (JSCM), Tokyo, Japan; National Hospital Organization Tochigi Medical Center, Tochigi, Japan.
  • Sato J; The Surveillance Committee of Japanese Society of Chemotherapy (JSC), The Japanese Association for Infectious Diseases (JAID) and The Japanese Society for Clinical Microbiology (JSCM), Tokyo, Japan.
  • Wakamura T; The Surveillance Committee of Japanese Society of Chemotherapy (JSC), The Japanese Association for Infectious Diseases (JAID) and The Japanese Society for Clinical Microbiology (JSCM), Tokyo, Japan.
  • Kiyota H; The Surveillance Committee of Japanese Society of Chemotherapy (JSC), The Japanese Association for Infectious Diseases (JAID) and The Japanese Society for Clinical Microbiology (JSCM), Tokyo, Japan.
  • Tateda K; The Surveillance Committee of Japanese Society of Chemotherapy (JSC), The Japanese Association for Infectious Diseases (JAID) and The Japanese Society for Clinical Microbiology (JSCM), Tokyo, Japan.
  • Hanaki H; Infection Control Research Center, Kitasato University, Tokyo, Japan.
  • Sakakibara N; Department of Dentistry and Oral Surgery, Nikko Memorial Hospital, Hokkaido, Japan.
  • Mizuno T; Department of Dentistry and Oral Surgery, Nikko Memorial Hospital, Hokkaido, Japan.
  • Miyajima H; Aizu Chuo Hospital, Fukushima, Japan.
  • Naito H; Iwaki City Medical Center, Fukushima, Japan.
  • Takagi R; Niigata University Medical & Dental Hospital, Niigata, Japan.
  • Kodama Y; Niigata University Medical & Dental Hospital, Niigata, Japan.
  • Yamaguchi A; Nippon Dental University Niigata Hospital, Niigata, Japan.
  • Akasiba R; Nippon Dental University Niigata Hospital, Niigata, Japan.
  • Yamane N; Ashikaga Red Cross Hospital, Tochigi, Japan.
  • Jinbu Y; Jichi Medical University Hospital, Tochigi, Japan.
  • Kusama M; Jichi Medical University Hospital, Tochigi, Japan.
  • Miyagi N; Nasu Red Cross Hospital, Tochigi, Japan.
  • Kato R; Kyowa Chuo Hospital, Ibaraki, Japan.
  • Nakatogawa N; Omitama City Medical Center, Ibaraki, Japan.
  • Izawa K; Ota Memorial Hospital, Gunma, Japan.
  • Tanzawa H; Chiba University Hospital, Chiba, Japan.
  • Kozu Y; Chiba University Hospital, Chiba, Japan.
  • Watanabe H; Yotsukaido Tokushukai Medical Center, Chiba, Japan.
  • Matsumoto K; Yotsukaido Tokushukai Medical Center, Chiba, Japan.
  • Shibahara T; Tokyo Dental College, Chiba, Japan.
  • Busujima Y; Tokyo Metropolitan Bokutoh Hospital, Tokyo, Japan.
  • Takato T; The University of Tokyo Hospital, Tokyo, Japan.
  • Sakamoto H; Tokai University Hachioji Hospital, Tokyo, Japan.
  • Watanabe D; Ikegami General Hospital, Tokyo, Japan.
  • Kubota H; Ikegami General Hospital, Tokyo, Japan.
  • Sasaki J; Jinkohkai Hospital, Kanagawa, Japan.
  • Uematsu M; Tohnoki Dental Clinic, Shizuoka, Japan.
  • Sasaki M; Shizuoka Medical Center, Shizuoka, Japan.
  • Kaetsu A; Toyohashi Municipal Hospital, Aichi, Japan.
  • Terasawa F; Toyohashi Municipal Hospital, Aichi, Japan.
  • Yura Y; Osaka University School of Dentistry, Osaka, Japan.
  • Iwai S; Osaka University School of Dentistry, Osaka, Japan.
  • Morita S; Osaka Dental University, Osaka, Japan.
  • Matsumoto K; Osaka Dental University, Osaka, Japan.
  • Oonishi T; Ikeda City Hospital, Osaka, Japan.
  • Komori T; Kobe University Hospital, Hyogo, Japan.
  • Furudoi S; Kobe University Hospital, Hyogo, Japan.
  • Fujibayashi J; Kobe Central Hospital, Hyogo, Japan.
  • Urade M; Hyogo College of Medicine Hospital, Hyogo, Japan.
  • Kishimoto H; Hyogo College of Medicine Hospital, Hyogo, Japan.
  • Yoshii T; Yoshii Dental and Oral Surgery Clinic, Hyogo, Japan.
  • Morihana T; Morihana Dental Clinic, Hyogo, Japan.
J Infect Chemother ; 26(9): 882-889, 2020 Sep.
Article em En | MEDLINE | ID: mdl-32591324
ABSTRACT
We report on the findings of the first antimicrobial susceptibility surveillance study in Japan of isolates recovered from odontogenic infections. Of the 38 facilities where patients representing the 4 groups of odontogenic infections were seen, 102 samples were collected from cases of periodontitis (group 1), 6 samples from pericoronitis (group 2), 84 samples from jaw inflammation (group 3) and 54 samples from phlegmon of the jaw bone area (group 4) for a total of 246 samples. The positivity rates of bacterial growth on culture were 85.3%, 100%, 84% and 88.9%, respectively, for groups 1, 2, 3 and 4. Streptococcus spp. isolation rates according to odontogenic infection group were 22% (group 1), 17.7% (group 3) and 20.7% (group 4). Anaerobic isolation rates were 66.9% (group 1), 71.8% (group 3) and 68.2% (group 4). Drug susceptibility tests were performed on 726 strains excluding 121 strains that were undergrown. The breakdown of the strains subjected to testing was 186 Streptococcus spp., 179 anaerobic gram-positive cocci, 246 Prevotella spp., 27 Porphyromonas spp., and 88 Fusobacterium spp. The isolates were tested against 30 antimicrobial agents. Sensitivities to penicillins and cephems were good except for Prevotella spp. The low sensitivities of Prevotella spp is due to ß-lactamase production. Prevotella strains resistant to macrolides, quinolones, and clindamycin were found. No strains resistant to carbapenems or penems were found among all strains tested. No anaerobic bacterial strain was resistant to metronidazole. Antimicrobial susceptibility testing performed on the S. anginosus group and anaerobic bacteria, which are the major pathogens associated with odontogenic infections, showed low MIC90 values to the penicillins which are the first-line antimicrobial agents for odontogenic infections; however, for Prevotella spp., penicillins combined with ß-lactamase inhibitor showed low MIC90 values.
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Infecções Bacterianas / Antibacterianos Tipo de estudo: Screening_studies Limite: Humans País/Região como assunto: Asia Idioma: En Revista: J Infect Chemother Ano de publicação: 2020 Tipo de documento: Article
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Infecções Bacterianas / Antibacterianos Tipo de estudo: Screening_studies Limite: Humans País/Região como assunto: Asia Idioma: En Revista: J Infect Chemother Ano de publicação: 2020 Tipo de documento: Article