Examination of preliminary behavioral and effective connectivity findings from treatment response to citalopram in cocaine use disorder: A dynamic causal modeling study.
Psychiatry Res Neuroimaging
; 303: 111127, 2020 09 30.
Article
em En
| MEDLINE
| ID: mdl-32593950
ABSTRACT
We sought effective (directional) connectivity parameters associated with response to citalopram in cocaine use disorder (CUD) by conducting a functional magnetic resonance imaging (fMRI) experiment with participants diagnosed with CUD (n = 13) and matched healthy controls (HC; n = 17). CUD participants showed a positive correlation between bilateral DLPFC-to-putamen effective connectivity and treatment effectiveness score. These preliminary results support further investigation of prefrontal-striatal interactions in response to treatment in CUD.
Palavras-chave
Texto completo:
1
Coleções:
01-internacional
Contexto em Saúde:
2_ODS3
Base de dados:
MEDLINE
Assunto principal:
Imageamento por Ressonância Magnética
/
Citalopram
/
Inibidores Seletivos de Recaptação de Serotonina
/
Córtex Pré-Frontal
/
Transtornos Relacionados ao Uso de Cocaína
/
Corpo Estriado
Tipo de estudo:
Diagnostic_studies
/
Prognostic_studies
Limite:
Adult
/
Female
/
Humans
/
Male
Idioma:
En
Revista:
Psychiatry Res Neuroimaging
Ano de publicação:
2020
Tipo de documento:
Article