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Genomic discovery of an evolutionarily programmed modality for small-molecule targeting of an intractable protein surface.
Shigdel, Uddhav K; Lee, Seung-Joo; Sowa, Mathew E; Bowman, Brian R; Robison, Keith; Zhou, Minyun; Pua, Khian Hong; Stiles, Dylan T; Blodgett, Joshua A V; Udwary, Daniel W; Rajczewski, Andrew T; Mann, Alan S; Mostafavi, Siavash; Hardy, Tara; Arya, Sukrat; Weng, Zhigang; Stewart, Michelle; Kenyon, Kyle; Morgenstern, Jay P; Pan, Ende; Gray, Daniel C; Pollock, Roy M; Fry, Andrew M; Klausner, Richard D; Townson, Sharon A; Verdine, Gregory L.
Afiliação
  • Shigdel UK; Warp Drive Bio, Inc., Redwood City, CA 94063.
  • Lee SJ; Warp Drive Bio, Inc., Redwood City, CA 94063.
  • Sowa ME; Warp Drive Bio, Inc., Redwood City, CA 94063.
  • Bowman BR; Warp Drive Bio, Inc., Redwood City, CA 94063.
  • Robison K; Warp Drive Bio, Inc., Redwood City, CA 94063.
  • Zhou M; Warp Drive Bio, Inc., Redwood City, CA 94063.
  • Pua KH; Warp Drive Bio, Inc., Redwood City, CA 94063.
  • Stiles DT; Warp Drive Bio, Inc., Redwood City, CA 94063.
  • Blodgett JAV; Warp Drive Bio, Inc., Redwood City, CA 94063.
  • Udwary DW; Warp Drive Bio, Inc., Redwood City, CA 94063.
  • Rajczewski AT; Warp Drive Bio, Inc., Redwood City, CA 94063.
  • Mann AS; Warp Drive Bio, Inc., Redwood City, CA 94063.
  • Mostafavi S; Warp Drive Bio, Inc., Redwood City, CA 94063.
  • Hardy T; Department of Molecular and Cell Biology, University of Leicester, LE1 7RH Leicester, United Kingdom.
  • Arya S; Department of Molecular and Cell Biology, University of Leicester, LE1 7RH Leicester, United Kingdom.
  • Weng Z; Warp Drive Bio, Inc., Redwood City, CA 94063.
  • Stewart M; Warp Drive Bio, Inc., Redwood City, CA 94063.
  • Kenyon K; Warp Drive Bio, Inc., Redwood City, CA 94063.
  • Morgenstern JP; Warp Drive Bio, Inc., Redwood City, CA 94063.
  • Pan E; Warp Drive Bio, Inc., Redwood City, CA 94063.
  • Gray DC; Warp Drive Bio, Inc., Redwood City, CA 94063.
  • Pollock RM; Warp Drive Bio, Inc., Redwood City, CA 94063.
  • Fry AM; Department of Molecular and Cell Biology, University of Leicester, LE1 7RH Leicester, United Kingdom.
  • Klausner RD; Lyell Immunopharma, South San Francisco, CA 94080; klausner.rick@gmail.com gregory_verdine@harvard.edu.
  • Townson SA; Warp Drive Bio, Inc., Redwood City, CA 94063.
  • Verdine GL; Warp Drive Bio, Inc., Redwood City, CA 94063; klausner.rick@gmail.com gregory_verdine@harvard.edu.
Proc Natl Acad Sci U S A ; 117(29): 17195-17203, 2020 07 21.
Article em En | MEDLINE | ID: mdl-32606248
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Antivirais / Genoma Bacteriano / Actinobacteria / Macrolídeos / Proteína 1A de Ligação a Tacrolimo / Bibliotecas de Moléculas Pequenas / Domínios e Motivos de Interação entre Proteínas Limite: Humans Idioma: En Revista: Proc Natl Acad Sci U S A Ano de publicação: 2020 Tipo de documento: Article
Texto completo
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Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Antivirais / Genoma Bacteriano / Actinobacteria / Macrolídeos / Proteína 1A de Ligação a Tacrolimo / Bibliotecas de Moléculas Pequenas / Domínios e Motivos de Interação entre Proteínas Limite: Humans Idioma: En Revista: Proc Natl Acad Sci U S A Ano de publicação: 2020 Tipo de documento: Article