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Novel FEMASK-score, a histopathologic assessment for destructive Charcot neuropathic arthropathy, reveals intraneural vasculopathy and correlates with progression and best treatment.
King, Jesse; Murie, Ben; Fanburg-Smith, Julie C; Stauch, Chris Michael; Flemming, Don; Klein, Michael J; Frauenhoffer, Elizabeth E; Fritsche, Madelaine; Smith, Jessica D; Elfar, John; Aynardi, Michael.
Afiliação
  • King J; Penn State College of Medicine, Penn State Health, Milton S. Hershey Medical Center, Hershey, PA, USA.
  • Murie B; Penn State College of Medicine, Penn State Health, Milton S. Hershey Medical Center, Hershey, PA, USA; Department of Pathology, Hershey, PA, USA.
  • Fanburg-Smith JC; Penn State College of Medicine, Penn State Health, Milton S. Hershey Medical Center, Hershey, PA, USA; Department of Pathology, Hershey, PA, USA; Department of Orthopedic Surgery, Hershey, PA, USA; Department of Pediatrics, Hershey, PA, USA. Electronic address: fourxjs@cox.net.
  • Stauch CM; Penn State College of Medicine, Penn State Health, Milton S. Hershey Medical Center, Hershey, PA, USA; Department of Orthopedic Surgery, Hershey, PA, USA.
  • Flemming D; Penn State College of Medicine, Penn State Health, Milton S. Hershey Medical Center, Hershey, PA, USA; Department of Radiology, Hershey, PA, USA.
  • Klein MJ; Hospital for Special Surgery, Pathology, New York, NY, USA.
  • Frauenhoffer EE; Penn State College of Medicine, Penn State Health, Milton S. Hershey Medical Center, Hershey, PA, USA; Department of Pathology, Hershey, PA, USA; Department of Orthopedic Surgery, Hershey, PA, USA.
  • Fritsche M; Penn State College of Medicine, Penn State Health, Milton S. Hershey Medical Center, Hershey, PA, USA.
  • Smith JD; Georgetown University, Washington DC, USA.
  • Elfar J; Penn State College of Medicine, Penn State Health, Milton S. Hershey Medical Center, Hershey, PA, USA; Department of Orthopedic Surgery, Hershey, PA, USA.
  • Aynardi M; Penn State College of Medicine, Penn State Health, Milton S. Hershey Medical Center, Hershey, PA, USA; Department of Orthopedic Surgery, Hershey, PA, USA.
Ann Diagn Pathol ; 47: 151509, 2020 Aug.
Article em En | MEDLINE | ID: mdl-32619921
BACKGROUND: Charcot neuropathic arthropathy is a debilitating, rapidly destructive degenerative joint disease that occurs in diabetic, neuropathic midfoot. Clinicoradiologic assessment for Charcot neuropathic arthropathy previously relied on Eichenholtz stage. There is limited histopathologic data on this entity. We wanted to independently develop a histopathologic scoring system for Charcot neuropathic arthropathy. DESIGN: Retrieval of surgical pathology midfoot specimens from Charcot patients (2012-2019) were analyzed to evaluate joint soft tissue and bone. Considering progression from large (≥half 40× hpf) to small (
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Artropatia Neurogênica / Sistema Nervoso Periférico / Pé Diabético / Pé Tipo de estudo: Etiology_studies / Prognostic_studies Limite: Adult / Aged / Aged80 / Female / Humans / Male / Middle aged Idioma: En Revista: Ann Diagn Pathol Ano de publicação: 2020 Tipo de documento: Article
Texto completo
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Artropatia Neurogênica / Sistema Nervoso Periférico / Pé Diabético / Pé Tipo de estudo: Etiology_studies / Prognostic_studies Limite: Adult / Aged / Aged80 / Female / Humans / Male / Middle aged Idioma: En Revista: Ann Diagn Pathol Ano de publicação: 2020 Tipo de documento: Article