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Therapeutic potential of novel Cell Division Cycle Kinase 7 inhibitors on TDP-43-related pathogenesis such as Frontotemporal Lobar Degeneration (FTLD) and amyotrophic lateral sclerosis (ALS).
Vaca, Gabriela; Martinez-Gonzalez, Loreto; Fernandez, Ana; Rojas-Prats, Elisa; Porras, Gracia; Cuevas, Eva P; Gil, Carmen; Martinez, Ana; Martin-Requero, Ángeles.
Afiliação
  • Vaca G; Department of Molecular Biomedicine, Centro de Investigaciones Biológicas, Margarita Salas (CSIC), Madrid, Spain.
  • Martinez-Gonzalez L; Department of Structural and Chemical Biology, Centro de Investigaciones Biológicas, Margarita Salas (CSIC), Madrid, Spain.
  • Fernandez A; Department of Molecular Biomedicine, Centro de Investigaciones Biológicas, Margarita Salas (CSIC), Madrid, Spain.
  • Rojas-Prats E; Department of Structural and Chemical Biology, Centro de Investigaciones Biológicas, Margarita Salas (CSIC), Madrid, Spain.
  • Porras G; Department of Molecular Biomedicine, Centro de Investigaciones Biológicas, Margarita Salas (CSIC), Madrid, Spain.
  • Cuevas EP; Department of Structural and Chemical Biology, Centro de Investigaciones Biológicas, Margarita Salas (CSIC), Madrid, Spain.
  • Gil C; Department of Structural and Chemical Biology, Centro de Investigaciones Biológicas, Margarita Salas (CSIC), Madrid, Spain.
  • Martinez A; Centro de Investigación Biomédica en Red de Enfermedades neurodegenerativas (CIBERNED), Instituto de Salud Carlos III, Madrid, Spain.
  • Martin-Requero Á; Department of Structural and Chemical Biology, Centro de Investigaciones Biológicas, Margarita Salas (CSIC), Madrid, Spain.
J Neurochem ; 156(3): 379-390, 2021 02.
Article em En | MEDLINE | ID: mdl-32628315
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Proteínas Quinases / Inibidores de Proteínas Quinases / Proteínas de Ligação a DNA / Degeneração Lobar Frontotemporal / Esclerose Lateral Amiotrófica Tipo de estudo: Etiology_studies Limite: Aged / Female / Humans / Male / Middle aged Idioma: En Revista: J Neurochem Ano de publicação: 2021 Tipo de documento: Article
Texto completo
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Proteínas Quinases / Inibidores de Proteínas Quinases / Proteínas de Ligação a DNA / Degeneração Lobar Frontotemporal / Esclerose Lateral Amiotrófica Tipo de estudo: Etiology_studies Limite: Aged / Female / Humans / Male / Middle aged Idioma: En Revista: J Neurochem Ano de publicação: 2021 Tipo de documento: Article