Measurement of liver blood flow in the rat using an 85Krypton clearance technique.
Br J Exp Pathol
; 58(3): 236-42, 1977 Jun.
Article
em En
| MEDLINE
| ID: mdl-326287
ABSTRACT
A method for the measurement of liver blood flow (LBF) in rats has been developed by recording the clearance of 85Kr from the liver after injection of a solution of the gas into the portal vein. This technique provides a measure of tissue perfusion at a cellular level. The animal preparation was maintained in a stable haemodynamic and respiratory state for up to 4-3 h by careful fluid and anaesthetic control. Stability of the model was reflected by relative constancy of the LBF measured throughout the experiment in all of the animals studied. The mean LBF determined in six rats was 2-41+/-(s.d.) 0-50 ml/g/min.
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Técnica de Diluição de Radioisótopos
/
Fígado
Limite:
Animals
Idioma:
En
Revista:
Br J Exp Pathol
Ano de publicação:
1977
Tipo de documento:
Article