Identification of histone malonylation in the human fetal brain and implications for diabetes-induced neural tube defects.

Zhang, Qin; Cai, Tanxi; Xiao, Zonghui; Li, Dan; Wan, Chunlei; Cui, Xiaodai; Bai, Baoling

Zhang, Qin; Cai, Tanxi; Xiao, Zonghui; Li, Dan; Wan, Chunlei; Cui, Xiaodai; Bai, Baoling.

Afiliação

Zhang Q; Beijing Municipal Key Laboratory of Child Development and Nutriomics, Capital Institute of Pediatrics, Beijing, China.
Cai T; Laboratory of Protein and Peptide Pharmaceuticals & Laboratory of Proteomics, Institute of Biophysics, Chinese Academy of Sciences, Beijing, China.
Xiao Z; Beijing Municipal Key Laboratory of Child Development and Nutriomics, Capital Institute of Pediatrics, Beijing, China.
Li D; Beijing Municipal Key Laboratory of Child Development and Nutriomics, Capital Institute of Pediatrics, Beijing, China.
Wan C; Weifang Medical University, Weifang, China.
Cui X; Beijing Municipal Key Laboratory of Child Development and Nutriomics, Capital Institute of Pediatrics, Beijing, China.
Bai B; Beijing Municipal Key Laboratory of Child Development and Nutriomics, Capital Institute of Pediatrics, Beijing, China.

Mol Genet Genomic Med ; 8(9): e1403, 2020 09.

Article em En | MEDLINE | ID: mdl-32666640

Assuntos

Histonas/metabolismo; Defeitos do Tubo Neural/metabolismo; Gravidez em Diabéticas/metabolismo; Processamento de Proteína Pós-Traducional; Animais; Encéfalo/embriologia; Encéfalo/metabolismo; Linhagem Celular; Epigênese Genética; Feminino; Humanos; Lisina/metabolismo; Masculino; Malonatos/metabolismo; Camundongos; Defeitos do Tubo Neural/genética; Defeitos do Tubo Neural/patologia; Gravidez

Palavras-chave

diabetes; histone lysine malonylation; mass spectrometry; neural tube defects

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Gravidez em Diabéticas / Histonas / Processamento de Proteína Pós-Traducional / Defeitos do Tubo Neural Tipo de estudo: Diagnostic_studies / Prognostic_studies / Risk_factors_studies Limite: Animals / Female / Humans / Male / Pregnancy Idioma: En Revista: Mol Genet Genomic Med Ano de publicação: 2020 Tipo de documento: Article

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