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Monte Carlo dosimetric characterization of a new high dose rate 169 Yb brachytherapy source and independent verification using a multipoint plastic scintillator detector.
Famulari, Gabriel; Linares Rosales, Haydee M; Dupere, Justine; Medich, David C; Beaulieu, Luc; Enger, Shirin A.
Afiliação
  • Famulari G; Medical Physics Unit, McGill University, Montreal, QC, H4A 3J1, Canada.
  • Linares Rosales HM; Département de physique, de génie physique et d'optique et Centre de recherche sur le cancer, Université Laval, QC, G1R 2J6, Canada.
  • Dupere J; Département de radio-oncologie et Axe Oncologie du CRCHU de Québec, CHU de Québec-Université Laval, QC, G1R 2J6, Canada.
  • Medich DC; Department of Physics, Worcester Polytechnic Institute, Worcester, MA, 01609, USA.
  • Beaulieu L; Department of Physics, Worcester Polytechnic Institute, Worcester, MA, 01609, USA.
  • Enger SA; Département de physique, de génie physique et d'optique et Centre de recherche sur le cancer, Université Laval, QC, G1R 2J6, Canada.
Med Phys ; 47(9): 4563-4573, 2020 Sep.
Article em En | MEDLINE | ID: mdl-32686145
ABSTRACT

PURPOSE:

A prototype 169 Yb source was developed in combination with a dynamic rotating platinum shield system (AIM-Brachy) to deliver intensity modulated brachytherapy (IMBT). The purpose of this study was to evaluate the dosimetric characteristics of the bare/shielded 169 Yb source using Monte Carlo (MC) simulations and perform an independent dose verification using a dosimetry platform based on a multipoint plastic scintillator detector (mPSD).

METHODS:

The TG-43U1 dosimetric parameters were calculated for the source model using RapidBrachyMCTPS. Real-time dose rate measurements were performed in a water tank for both the bare/shielded source using a custom remote afterloader. For each dwell position, the dose rate was independently measured by the three scintillators (BCF-10, BCF-12, and BCF-60). For the bare source, dose rate was measured at distances up to 3 cm away from the source over a range of 7 cm along the catheter. For the shielded source, measurements were performed with the mPSD placed at 1 cm from the source at four different azimuthal angles ( 0 ∘ , 9 0 ∘ , 18 0 ∘ , and 27 0 ∘ ).

RESULTS:

The dosimetric parameters were tabulated for the source model. For the bare source, differences between measured and calculated along-away dose rates were generally below 5-10%. Along the transverse axis, deviations were, on average (range), 3.3% (0.6-6.2%) for BCF-10, 1.7% (0.9-2.9%) for BCF-12, and 2.2% (0.3-4.4%) for BCF-60. The maximum dose rate reduction due to shielding at a radial distance of 1 cm was 88.8 ± 1.2%, compared to 83.5 ± 0.5% as calculated by MC.

CONCLUSIONS:

The dose distribution for the bare/shielded 169 Yb source was independently verified using mPSD with good agreement in regions close to the source. The 169 Yb source coupled with the partial-shielding system is an effective technique to deliver IMBT.
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Texto completo: 1 Coleções: 01-internacional Contexto em Saúde: 1_ASSA2030 Base de dados: MEDLINE Assunto principal: Braquiterapia Tipo de estudo: Health_economic_evaluation / Prognostic_studies Idioma: En Revista: Med Phys Ano de publicação: 2020 Tipo de documento: Article

Texto completo: 1 Coleções: 01-internacional Contexto em Saúde: 1_ASSA2030 Base de dados: MEDLINE Assunto principal: Braquiterapia Tipo de estudo: Health_economic_evaluation / Prognostic_studies Idioma: En Revista: Med Phys Ano de publicação: 2020 Tipo de documento: Article