Quantification of surface composition and surface structure of inhalation powders using TOF-SIMS.

Nicholas, Mark; Josefson, Mats; Fransson, Magnus; Wilbs, Jonas; Roos, Carl; Boissier, Catherine; Thalberg, Kyrre

Nicholas, Mark; Josefson, Mats; Fransson, Magnus; Wilbs, Jonas; Roos, Carl; Boissier, Catherine; Thalberg, Kyrre.

Afiliação

Nicholas M; AstraZeneca Pharmaceutical Technology & Development, Gothenburg, Sweden. Electronic address: Mark.Nicholas@astrazeneca.com.
Josefson M; AstraZeneca Pharmaceutical Technology & Development, Gothenburg, Sweden.
Fransson M; AstraZeneca Pharmaceutical Technology & Development, Gothenburg, Sweden.
Wilbs J; AstraZeneca Pharmaceutical Technology & Development, Gothenburg, Sweden.
Roos C; AstraZeneca Pharmaceutical Technology & Development, Gothenburg, Sweden.
Boissier C; AstraZeneca Pharmaceutical Technology & Development, Gothenburg, Sweden.
Thalberg K; AstraZeneca Pharmaceutical Technology & Development, Gothenburg, Sweden. Electronic address: Kyrre.Thalberg@astrazeneca.com.

Int J Pharm ; 587: 119666, 2020 Sep 25.

Article em En | MEDLINE | ID: mdl-32702450

Assuntos

Portadores de Fármacos; Lactose; Administração por Inalação; Aerossóis; Tamanho da Partícula; Pós; Propriedades de Superfície

Palavras-chave

Dry powders; Imaging; Inhalation; Multivariate analysis; Surface quantification; TOF-SIMS; XPS

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Portadores de Fármacos / Lactose Idioma: En Revista: Int J Pharm Ano de publicação: 2020 Tipo de documento: Article

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