An innovative sampling approach combined with liquid chromatography-tandem mass spectrometry for the analysis of emerging pollutants in drinking water.
J Mass Spectrom
; 55(11): e4608, 2020 Nov.
Article
em En
| MEDLINE
| ID: mdl-32707599
ABSTRACT
In this work, an innovative sampling and preconcentration method followed by analysis with liquid chromatography coupled to tandem mass spectrometry with electrospray ionization (LC-ESI-MS/MS) was developed for the determination of different emerging pollutants (five anti-inflammatory drugs and one antibacterial agent) in water matrices. Thin-film microextraction blades, consisting of stainless steel blades with a coating made of divinylbenzene, have been employed. The blades, fixed onto a stainless steel support, were mounted on a laboratory stirrer with adjustable speed, immersed in water samples and eluted with methanol. The analytical procedure was developed, carefully optimizing stirring speed and extraction time. A good reproducibility among the blades was observed; quantitation limits at the ng L-1 level were achieved. Calibration curves were constructed by applying the whole procedure to tap water samples, free from analytes, spiked with standards in the concentration range 0.01-2 µg L-1 ; good linearity was obtained, with R2 between 0.9984 and 0.9991. The optimized method was applied to tap and surface waters; two anti-inflammatory drugs were detected at the ng L-1 level in surface water. In one sample, diclofenac and naproxen were measured at 26 ± 5 and 15 ± 1 ng L-1 , respectively; only diclofenac was quantified in the other sample at 14 ± 3 ng L-1 .
Palavras-chave
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Poluentes Químicos da Água
/
Água Potável
/
Anti-Inflamatórios
/
Antibacterianos
Idioma:
En
Revista:
J Mass Spectrom
Ano de publicação:
2020
Tipo de documento:
Article