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Design, synthesis ADMET and molecular docking of new imidazo[4,5-b]pyridine-5-thione derivatives as potential tyrosyl-tRNA synthetase inhibitors.
Othman, Ismail M M; Gad-Elkareem, Mohamed A M; Hassane Anouar, El; Aouadi, Kaïss; Kadri, Adel; Snoussi, Mejdi.
Afiliação
  • Othman IMM; Department of Chemistry, Faculty of Science, Al-Azhar University, Assiut 71524, Egypt.
  • Gad-Elkareem MAM; Department of Chemistry, Faculty of Science, Al-Azhar University, Assiut 71524, Egypt; Faculty of Science and Arts in Baljurashi, Albaha University, P.O. Box (1988), Albaha, Saudi Arabia.
  • Hassane Anouar E; Department of Chemistry, College of Science and Humanities in Al-Kharj, Prince Sattam bin Abdulaziz University, Al-Kharj 11942, Saudi Arabia.
  • Aouadi K; Department of Chemistry, College of Science, Qassim University, Buraidah 51452, Saudi Arabia; University of Monastir, Faculty of Sciences of Monastir, Avenue of the Environment, 5019 Monastir, Tunisia.
  • Kadri A; Faculty of Science and Arts in Baljurashi, Albaha University, P.O. Box (1988), Albaha, Saudi Arabia; Faculty of Science of Sfax, Department of Chemistry, University of Sfax, B.P. 1171, 3000 Sfax, Tunisia. Electronic address: lukadel@yahoo.fr.
  • Snoussi M; Department of Biology, College of Science, Hail, P.O. 2440, University of Ha'il City 2440, Saudi Arabia; Laboratory of Genetics, Biodiversity and Valorization of Bio-resources (LR11ES41), University of Monastir, Higher Institute of Biotechnology of Monastir, Avenue Tahar Haddad, BP74, 5000 Monastir,
Bioorg Chem ; 102: 104105, 2020 09.
Article em En | MEDLINE | ID: mdl-32717689
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Texto completo: 1 Coleções: 01-internacional Contexto em Saúde: 3_ND Base de dados: MEDLINE Assunto principal: Staphylococcus aureus / Tirosina-tRNA Ligase / Inibidores Enzimáticos / Simulação de Acoplamento Molecular / Antibacterianos / Antifúngicos Tipo de estudo: Prognostic_studies Idioma: En Revista: Bioorg Chem Ano de publicação: 2020 Tipo de documento: Article
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Texto completo: 1 Coleções: 01-internacional Contexto em Saúde: 3_ND Base de dados: MEDLINE Assunto principal: Staphylococcus aureus / Tirosina-tRNA Ligase / Inibidores Enzimáticos / Simulação de Acoplamento Molecular / Antibacterianos / Antifúngicos Tipo de estudo: Prognostic_studies Idioma: En Revista: Bioorg Chem Ano de publicação: 2020 Tipo de documento: Article