Tonicity-responsive enhancer-binding protein promotes stemness of liver cancer and cisplatin resistance.

Lee, Jun Ho; Suh, Jae Hee; Kang, Hyun Je; Choi, Soo Youn; Jung, Seok Won; Lee-Kwon, Whaseon; Park, Soo-Ah; Kim, Hajin; Ye, Byeong Jin; Yoo, Eun Jin; Jeong, Gyu Won; Park, Neung Hwa; Kwon, Hyug Moo

Lee, Jun Ho; Suh, Jae Hee; Kang, Hyun Je; Choi, Soo Youn; Jung, Seok Won; Lee-Kwon, Whaseon; Park, Soo-Ah; Kim, Hajin; Ye, Byeong Jin; Yoo, Eun Jin; Jeong, Gyu Won; Park, Neung Hwa; Kwon, Hyug Moo.

Afiliação

Lee JH; School of Life Sciences, Ulsan National Institute of Science and Technology, Ulsan, 44919, Republic of Korea.
Suh JH; Department of Pathology, University of Ulsan College of Medicine, Ulsan University Hospital, Ulsan 44033, Republic of Korea.
Kang HJ; School of Life Sciences, Ulsan National Institute of Science and Technology, Ulsan, 44919, Republic of Korea.
Choi SY; School of Life Sciences, Ulsan National Institute of Science and Technology, Ulsan, 44919, Republic of Korea.
Jung SW; Department of Internal Medicine, University of Ulsan College of Medicine, Ulsan University Hospital, Ulsan 44033, Republic of Korea.
Lee-Kwon W; School of Life Sciences, Ulsan National Institute of Science and Technology, Ulsan, 44919, Republic of Korea.
Park SA; School of Life Sciences, Ulsan National Institute of Science and Technology, Ulsan, 44919, Republic of Korea.
Kim H; School of Life Sciences, Ulsan National Institute of Science and Technology, Ulsan, 44919, Republic of Korea.
Ye BJ; School of Life Sciences, Ulsan National Institute of Science and Technology, Ulsan, 44919, Republic of Korea.
Yoo EJ; School of Life Sciences, Ulsan National Institute of Science and Technology, Ulsan, 44919, Republic of Korea.
Jeong GW; School of Life Sciences, Ulsan National Institute of Science and Technology, Ulsan, 44919, Republic of Korea.
Park NH; Department of Internal Medicine, University of Ulsan College of Medicine, Ulsan University Hospital, Ulsan 44033, Republic of Korea. Electronic address: nhparkmd@gmail.com.
Kwon HM; School of Life Sciences, Ulsan National Institute of Science and Technology, Ulsan, 44919, Republic of Korea. Electronic address: hmkwon@unist.ac.kr.

EBioMedicine ; 58: 102926, 2020 Aug.

Article em En | MEDLINE | ID: mdl-32739873

Assuntos

Carcinoma Hepatocelular/patologia; Proteínas de Ligação a DNA/metabolismo; Resistencia a Medicamentos Antineoplásicos; Endonucleases/metabolismo; Neoplasias Hepáticas/patologia; Células-Tronco Neoplásicas/patologia; Fatores de Transcrição/genética; Animais; Biomarcadores Tumorais/metabolismo; Carcinoma Hepatocelular/genética; Carcinoma Hepatocelular/metabolismo; Linhagem Celular Tumoral; Cisplatino/farmacologia; Feminino; Regulação Neoplásica da Expressão Gênica; Humanos; Neoplasias Hepáticas/genética; Neoplasias Hepáticas/metabolismo; Masculino; Camundongos; Camundongos Endogâmicos BALB C; Camundongos Nus; Pessoa de Meia-Idade; Células-Tronco Neoplásicas/metabolismo; Prognóstico; Regulação para Cima; Ensaios Antitumorais Modelo de Xenoenxerto

Palavras-chave

ERCC1/XPF; Hepatocellular carcinoma recurrence; NF-κB; SOX2

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Fatores de Transcrição / Células-Tronco Neoplásicas / Carcinoma Hepatocelular / Resistencia a Medicamentos Antineoplásicos / Proteínas de Ligação a DNA / Endonucleases / Neoplasias Hepáticas Tipo de estudo: Prognostic_studies Limite: Animals / Female / Humans / Male / Middle aged Idioma: En Revista: EBioMedicine Ano de publicação: 2020 Tipo de documento: Article

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