A sandwich-type surface-enhanced Raman scattering sensor using dual aptamers and gold nanoparticles for the detection of tumor extracellular vesicles.

Hou, Min; He, Dinggeng; Bu, Hongchang; Wang, Huizhen; Huang, Jin; Gu, Jinqing; Wu, Ri; Li, Hung-Wing; He, Xiaoxiao; Wang, Kemin

Hou, Min; He, Dinggeng; Bu, Hongchang; Wang, Huizhen; Huang, Jin; Gu, Jinqing; Wu, Ri; Li, Hung-Wing; He, Xiaoxiao; Wang, Kemin.

Afiliação

Hou M; State Key Laboratory of Chemo/Biosensing and Chemometrics, College of Biology, College of Chemistry and Chemical Engineering, Hunan University, Key Laboratory for Bio-Nanotechnology and Molecular Engineering of Hunan Province, Changsha 410082, China. hedinggeng@hnu.edu.cn xiaoxiaohe@hnu.edu.cn kmwang@hnu.edu.cn.

Analyst ; 145(19): 6232-6236, 2020 Sep 28.

Article em En | MEDLINE | ID: mdl-32744556

ABSTRACT

ABSTRACT

A sandwich-type surface-enhanced Raman scattering (SERS) sensor using dual aptamers and gold-enhanced Raman signal probes has been successfully constructed for the detection of tumor-derived extracellular vesicles. The simple and sensitive sensor has the capability to detect tumor extracellular vesicles in 10-fold diluted human serum samples.

Assuntos

Vesículas Extracelulares; Nanopartículas Metálicas; Neoplasias; Ouro; Humanos; Neoplasias/diagnóstico; Análise Espectral Raman

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Nanopartículas Metálicas / Vesículas Extracelulares / Neoplasias Tipo de estudo: Diagnostic_studies Limite: Humans Idioma: En Revista: Analyst Ano de publicação: 2020 Tipo de documento: Article

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