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Topoisomerase 1 prevents replication stress at R-loop-enriched transcription termination sites.
Promonet, Alexy; Padioleau, Ismaël; Liu, Yaqun; Sanz, Lionel; Biernacka, Anna; Schmitz, Anne-Lyne; Skrzypczak, Magdalena; Sarrazin, Amélie; Mettling, Clément; Rowicka, Maga; Ginalski, Krzysztof; Chedin, Frédéric; Chen, Chun-Long; Lin, Yea-Lih; Pasero, Philippe.
Afiliação
  • Promonet A; Institut de Génétique Humaine, CNRS et Université de Montpellier, Equipe labélisée Ligue contre le Cancer, Montpellier, France.
  • Padioleau I; Institut de Génétique Humaine, CNRS et Université de Montpellier, Equipe labélisée Ligue contre le Cancer, Montpellier, France.
  • Liu Y; Institut Gustave Roussy, Villejuif, France.
  • Sanz L; Institut Curie, PSL Research University, CNRS, UMR3244, Sorbonne Université, Paris, France.
  • Biernacka A; Department of Molecular and Cellular Biology, University of California, Davis, CA, 95616, USA.
  • Schmitz AL; Laboratory of Bioinformatics and Systems Biology, Centre of New Technologies, University of Warsaw, Warsaw, Poland.
  • Skrzypczak M; Institut de Génétique Humaine, CNRS et Université de Montpellier, Equipe labélisée Ligue contre le Cancer, Montpellier, France.
  • Sarrazin A; Laboratory of Bioinformatics and Systems Biology, Centre of New Technologies, University of Warsaw, Warsaw, Poland.
  • Mettling C; BioCampus Montpellier, CNRS et Université de Montpellier, Montpellier, France.
  • Rowicka M; Institut de Génétique Humaine, CNRS et Université de Montpellier, Montpellier, France.
  • Ginalski K; Department of Biochemistry and Molecular Biology, University of Texas Medical Branch at Galveston, Galveston, TX, USA.
  • Chedin F; Laboratory of Bioinformatics and Systems Biology, Centre of New Technologies, University of Warsaw, Warsaw, Poland.
  • Chen CL; Department of Molecular and Cellular Biology, University of California, Davis, CA, 95616, USA.
  • Lin YL; Institut Curie, PSL Research University, CNRS, UMR3244, Sorbonne Université, Paris, France. chunlong.chen@curie.fr.
  • Pasero P; Institut de Génétique Humaine, CNRS et Université de Montpellier, Equipe labélisée Ligue contre le Cancer, Montpellier, France. yea-lih.lin@igh.cnrs.fr.
Nat Commun ; 11(1): 3940, 2020 08 07.
Article em En | MEDLINE | ID: mdl-32769985
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Transcrição Gênica / Regiões Terminadoras Genéticas / DNA Topoisomerases Tipo I / Replicação do DNA / Estruturas R-Loop Limite: Humans Idioma: En Revista: Nat Commun Ano de publicação: 2020 Tipo de documento: Article
Texto completo
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Transcrição Gênica / Regiões Terminadoras Genéticas / DNA Topoisomerases Tipo I / Replicação do DNA / Estruturas R-Loop Limite: Humans Idioma: En Revista: Nat Commun Ano de publicação: 2020 Tipo de documento: Article