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In vitro Cas9-assisted editing of modular polyketide synthase genes to produce desired natural product derivatives.
Kudo, Kei; Hashimoto, Takuya; Hashimoto, Junko; Kozone, Ikuko; Kagaya, Noritaka; Ueoka, Reiko; Nishimura, Takehiro; Komatsu, Mamoru; Suenaga, Hikaru; Ikeda, Haruo; Shin-Ya, Kazuo.
Afiliação
  • Kudo K; National Institute of Advanced Industrial Science and Technology (AIST), 2-4-7 Aomi, Koto-ku, Tokyo, Japan.
  • Hashimoto T; National Institute of Advanced Industrial Science and Technology (AIST), 2-4-7 Aomi, Koto-ku, Tokyo, Japan.
  • Hashimoto J; Japan Biological Informatics Consortium (JBIC), 2-4-32 Aomi, Koto-ku, Tokyo, Japan.
  • Kozone I; Japan Biological Informatics Consortium (JBIC), 2-4-32 Aomi, Koto-ku, Tokyo, Japan.
  • Kagaya N; National Institute of Advanced Industrial Science and Technology (AIST), 2-4-7 Aomi, Koto-ku, Tokyo, Japan.
  • Ueoka R; National Institute of Advanced Industrial Science and Technology (AIST), 2-4-7 Aomi, Koto-ku, Tokyo, Japan.
  • Nishimura T; Technology Research Association for Next Generation Natural Products Chemistry, 2-4-7 Aomi, Koto-ku, Tokyo, Japan.
  • Komatsu M; Kitasato Institute for Life Sciences, Kitasato University, 1-15-1 Kitasato, Minami-ku, Sagamihara, Kanagawa, Japan.
  • Suenaga H; National Institute of Advanced Industrial Science and Technology (AIST), 2-4-7 Aomi, Koto-ku, Tokyo, Japan.
  • Ikeda H; Kitasato Institute for Life Sciences, Kitasato University, 1-15-1 Kitasato, Minami-ku, Sagamihara, Kanagawa, Japan. ikeda@ls.kitasato-u.ac.jp.
  • Shin-Ya K; National Institute of Advanced Industrial Science and Technology (AIST), 2-4-7 Aomi, Koto-ku, Tokyo, Japan. k-shinya@aist.go.jp.
Nat Commun ; 11(1): 4022, 2020 08 11.
Article em En | MEDLINE | ID: mdl-32782248
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Policetídeo Sintases / Sistemas CRISPR-Cas / Edição de Genes Idioma: En Revista: Nat Commun Ano de publicação: 2020 Tipo de documento: Article
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Policetídeo Sintases / Sistemas CRISPR-Cas / Edição de Genes Idioma: En Revista: Nat Commun Ano de publicação: 2020 Tipo de documento: Article