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Structure-Activity Relationship Studies of α-Ketoamides as Inhibitors of the Phospholipase A and Acyltransferase Enzyme Family.
Zhou, Juan; Mock, Elliot D; Al Ayed, Karol; Di, Xinyu; Kantae, Vasudev; Burggraaff, Lindsey; Stevens, Anna F; Martella, Andrea; Mohr, Florian; Jiang, Ming; van der Wel, Tom; Wendel, Tiemen J; Ofman, Tim P; Tran, Yvonne; de Koster, Nicky; van Westen, Gerard J P; Hankemeier, Thomas; van der Stelt, Mario.
Afiliação
  • Zhou J; Department of Molecular Physiology, Leiden Institute of Chemistry, Leiden University & Oncode Institute, 2300 RA Leiden, The Netherlands.
  • Mock ED; Department of Molecular Physiology, Leiden Institute of Chemistry, Leiden University & Oncode Institute, 2300 RA Leiden, The Netherlands.
  • Al Ayed K; Department of Molecular Physiology, Leiden Institute of Chemistry, Leiden University & Oncode Institute, 2300 RA Leiden, The Netherlands.
  • Di X; Department of Systems Biomedicine and Pharmacology, Leiden Academic Centre for Drug Research, Leiden University, 2300 RA Leiden, The Netherlands.
  • Kantae V; Department of Systems Biomedicine and Pharmacology, Leiden Academic Centre for Drug Research, Leiden University, 2300 RA Leiden, The Netherlands.
  • Burggraaff L; Department of Drug Discovery and Safety, Leiden Academic Centre for Drug Research, Leiden University, 2300 RA Leiden, The Netherlands.
  • Stevens AF; Department of Molecular Physiology, Leiden Institute of Chemistry, Leiden University & Oncode Institute, 2300 RA Leiden, The Netherlands.
  • Martella A; Department of Molecular Physiology, Leiden Institute of Chemistry, Leiden University & Oncode Institute, 2300 RA Leiden, The Netherlands.
  • Mohr F; Department of Molecular Physiology, Leiden Institute of Chemistry, Leiden University & Oncode Institute, 2300 RA Leiden, The Netherlands.
  • Jiang M; Department of Molecular Physiology, Leiden Institute of Chemistry, Leiden University & Oncode Institute, 2300 RA Leiden, The Netherlands.
  • van der Wel T; Department of Molecular Physiology, Leiden Institute of Chemistry, Leiden University & Oncode Institute, 2300 RA Leiden, The Netherlands.
  • Wendel TJ; Department of Molecular Physiology, Leiden Institute of Chemistry, Leiden University & Oncode Institute, 2300 RA Leiden, The Netherlands.
  • Ofman TP; Department of Molecular Physiology, Leiden Institute of Chemistry, Leiden University & Oncode Institute, 2300 RA Leiden, The Netherlands.
  • Tran Y; Department of Molecular Physiology, Leiden Institute of Chemistry, Leiden University & Oncode Institute, 2300 RA Leiden, The Netherlands.
  • de Koster N; Department of Molecular Physiology, Leiden Institute of Chemistry, Leiden University & Oncode Institute, 2300 RA Leiden, The Netherlands.
  • van Westen GJP; Department of Drug Discovery and Safety, Leiden Academic Centre for Drug Research, Leiden University, 2300 RA Leiden, The Netherlands.
  • Hankemeier T; Department of Systems Biomedicine and Pharmacology, Leiden Academic Centre for Drug Research, Leiden University, 2300 RA Leiden, The Netherlands.
  • van der Stelt M; Department of Molecular Physiology, Leiden Institute of Chemistry, Leiden University & Oncode Institute, 2300 RA Leiden, The Netherlands.
J Med Chem ; 63(17): 9340-9359, 2020 09 10.
Article em En | MEDLINE | ID: mdl-32787138
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Fosfolipases / Aciltransferases / Inibidores Enzimáticos / Amidas Limite: Humans Idioma: En Revista: J Med Chem Ano de publicação: 2020 Tipo de documento: Article
Texto completo
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Fosfolipases / Aciltransferases / Inibidores Enzimáticos / Amidas Limite: Humans Idioma: En Revista: J Med Chem Ano de publicação: 2020 Tipo de documento: Article