Coronavirus Spectrum Infections (COVID-19, MERS, SARS) in Cancer Patients: A Systematic Review of the Literature.
Cancer Invest
; 38(8-9): 436-444, 2020 Sep.
Article
em En
| MEDLINE
| ID: mdl-32787597
ABSTRACT
BACKGROUND:
Coronavirus 2019 (COVID-19) has spread rapidly around the world to become a global pandemic. There is limited data on the impact of COVID-19 among patients with cancer.METHODS:
A systematic review was performed to determine outcomes of adult patients with cancer affected by coronavirus infections, specifically SARS, MERS, and COVID-19. Studies were independently screened by two reviewers and assessed for quality and bias. Outcomes measured included study characteristics, cancer type, phase of care at the time of diagnosis, and clinical presentation. Morbidity and mortality outcomes were analyzed to assess the severity of infection as compared to the general population.RESULTS:
A total of 19 studies with 110 patients were included. Of these, 66.4% had COVID-19 infections, 32.7% MERS and only one patient with SARS. The majority of COVID-19 studies were based on studies in China. There was a 56.6% rate of a severe event, including ICU admission or requiring mechanical ventilation, with an overall 44.5% fatality rate.CONCLUSIONS:
Patients with cancer with coronavirus infections may be more susceptible to higher morbidity and mortality.Palavras-chave
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Infecções por Coronavirus
/
Neoplasias
Tipo de estudo:
Systematic_reviews
Limite:
Adult
/
Humans
País/Região como assunto:
Asia
Idioma:
En
Revista:
Cancer Invest
Ano de publicação:
2020
Tipo de documento:
Article