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The m6A RNA demethylase FTO is a HIF-independent synthetic lethal partner with the VHL tumor suppressor.
Xiao, Yiren; Thakkar, Kaushik N; Zhao, Hongjuan; Broughton, James; Li, Yang; Seoane, Jose A; Diep, Anh N; Metzner, Thomas J; von Eyben, Rie; Dill, David L; Brooks, James D; Curtis, Christina; Leppert, John T; Ye, Jiangbin; Peehl, Donna M; Giaccia, Amato J; Sinha, Subarna; Rankin, Erinn B.
Afiliação
  • Xiao Y; Department of Radiation Oncology, Stanford University, Stanford, CA 94305.
  • Thakkar KN; Department of Radiation Oncology, Stanford University, Stanford, CA 94305.
  • Zhao H; Department of Urology, Stanford University, Stanford, CA 94305.
  • Broughton J; Mammoth Biosciences, South San Francisco, CA 94080.
  • Li Y; Department of Radiation Oncology, Stanford University, Stanford, CA 94305.
  • Seoane JA; Department of Medicine, Stanford University, Stanford, CA 94305.
  • Diep AN; Deparment of Genetics, Stanford University, Stanford, CA 94305.
  • Metzner TJ; Department of Radiation Oncology, Stanford University, Stanford, CA 94305.
  • von Eyben R; Department of Urology, Stanford University, Stanford, CA 94305.
  • Dill DL; Department of Radiation Oncology, Stanford University, Stanford, CA 94305.
  • Brooks JD; Department of Computer Science, Stanford University, Stanford, CA 94305.
  • Curtis C; Department of Urology, Stanford University, Stanford, CA 94305.
  • Leppert JT; Department of Medicine, Stanford University, Stanford, CA 94305.
  • Ye J; Deparment of Genetics, Stanford University, Stanford, CA 94305.
  • Peehl DM; Department of Urology, Stanford University, Stanford, CA 94305.
  • Giaccia AJ; Department of Radiation Oncology, Stanford University, Stanford, CA 94305.
  • Sinha S; Deparment of Genetics, Stanford University, Stanford, CA 94305.
  • Rankin EB; Department of Radiology and Biomedical Imaging, University of California, San Francisco, CA 94158.
Proc Natl Acad Sci U S A ; 117(35): 21441-21449, 2020 09 01.
Article em En | MEDLINE | ID: mdl-32817424
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Carcinoma de Células Renais / Proteína Supressora de Tumor Von Hippel-Lindau / Dioxigenase FTO Dependente de alfa-Cetoglutarato / Mutações Sintéticas Letais / Neoplasias Renais Tipo de estudo: Prognostic_studies Limite: Animals / Humans Idioma: En Revista: Proc Natl Acad Sci U S A Ano de publicação: 2020 Tipo de documento: Article
Texto completo
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Carcinoma de Células Renais / Proteína Supressora de Tumor Von Hippel-Lindau / Dioxigenase FTO Dependente de alfa-Cetoglutarato / Mutações Sintéticas Letais / Neoplasias Renais Tipo de estudo: Prognostic_studies Limite: Animals / Humans Idioma: En Revista: Proc Natl Acad Sci U S A Ano de publicação: 2020 Tipo de documento: Article