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Structural basis for antibiotic action of the B1 antivitamin 2'-methoxy-thiamine.
Rabe von Pappenheim, Fabian; Aldeghi, Matteo; Shome, Brateen; Begley, Tadhg; de Groot, Bert L; Tittmann, Kai.
Afiliação
  • Rabe von Pappenheim F; Department of Molecular Enzymology, Göttingen Center of Molecular Biosciences, University of Göttingen, Göttingen, Germany.
  • Aldeghi M; Department of Structural Dynamics, Max Planck Institute for Biophysical Chemistry, Göttingen, Germany.
  • Shome B; Research Group of Computational Biomolecular Dynamics, Max Planck Institute for Biophysical Chemistry, Göttingen, Germany.
  • Begley T; Department of Chemistry, Texas A&M University, College Station, TX, USA.
  • de Groot BL; Department of Chemistry, Texas A&M University, College Station, TX, USA.
  • Tittmann K; Research Group of Computational Biomolecular Dynamics, Max Planck Institute for Biophysical Chemistry, Göttingen, Germany. bgroot@gwdg.de.
Nat Chem Biol ; 16(11): 1237-1245, 2020 11.
Article em En | MEDLINE | ID: mdl-32839604
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Texto completo: 1 Coleções: 01-internacional Contexto em Saúde: 3_ND Base de dados: MEDLINE Assunto principal: Tiamina / Transcetolase / Inibidores Enzimáticos / Antibacterianos Limite: Humans Idioma: En Revista: Nat Chem Biol Ano de publicação: 2020 Tipo de documento: Article
Texto completo
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Texto completo: 1 Coleções: 01-internacional Contexto em Saúde: 3_ND Base de dados: MEDLINE Assunto principal: Tiamina / Transcetolase / Inibidores Enzimáticos / Antibacterianos Limite: Humans Idioma: En Revista: Nat Chem Biol Ano de publicação: 2020 Tipo de documento: Article