The Phage-Encoded <i>N</i>-Acetyltransferase Rac Mediates Inactivation of <i>Pseudomonas aeruginosa</i> Transcription by Cleavage of the RNA Polymerase Alpha Subunit.

Ceyssens, Pieter-Jan; De Smet, Jeroen; Wagemans, Jeroen; Akulenko, Natalia; Klimuk, Evgeny; Hedge, Subray; Voet, Marleen; Hendrix, Hanne; Paeshuyse, Jan; Landuyt, Bart; Xu, Hua; Blanchard, John; Severinov, Konstantin; Lavigne, Rob

The Phage-Encoded N-Acetyltransferase Rac Mediates Inactivation of Pseudomonas aeruginosa Transcription by Cleavage of the RNA Polymerase Alpha Subunit.

Ceyssens, Pieter-Jan; De Smet, Jeroen; Wagemans, Jeroen; Akulenko, Natalia; Klimuk, Evgeny; Hedge, Subray; Voet, Marleen; Hendrix, Hanne; Paeshuyse, Jan; Landuyt, Bart; Xu, Hua; Blanchard, John; Severinov, Konstantin; Lavigne, Rob.

Afiliação

Ceyssens PJ; Department of Biosystems, KU Leuven, 3000 Leuven, Belgium.
De Smet J; Department of Biosystems, KU Leuven, 3000 Leuven, Belgium.
Wagemans J; Department of Biosystems, KU Leuven, 3000 Leuven, Belgium.
Akulenko N; Institute of Molecular Genetics, Russian Academy of Sciences, 119334 Moscow, Russia.
Klimuk E; Institute of Molecular Genetics, Russian Academy of Sciences, 119334 Moscow, Russia.
Hedge S; Department of Biochemistry, Albert Einstein College of Medicine, New York, NY 10461, USA.
Voet M; Department of Biosystems, KU Leuven, 3000 Leuven, Belgium.
Hendrix H; Department of Biosystems, KU Leuven, 3000 Leuven, Belgium.
Paeshuyse J; Department of Biosystems, KU Leuven, 3000 Leuven, Belgium.
Landuyt B; Department of Biology, KU Leuven, 3000 Leuven, Belgium.
Xu H; Department of Biochemistry, Albert Einstein College of Medicine, New York, NY 10461, USA.
Blanchard J; Department of Biochemistry, Albert Einstein College of Medicine, New York, NY 10461, USA.
Severinov K; Institute of Molecular Genetics, Russian Academy of Sciences, 119334 Moscow, Russia.
Lavigne R; Department of Biosystems, KU Leuven, 3000 Leuven, Belgium.

Viruses ; 12(9)2020 09 02.

Article em En | MEDLINE | ID: mdl-32887488

Assuntos

Acetiltransferases/metabolismo; Proteínas de Bactérias/metabolismo; RNA Polimerases Dirigidas por DNA/metabolismo; Fagos de Pseudomonas/enzimologia; Pseudomonas aeruginosa/enzimologia; Pseudomonas aeruginosa/virologia; Proteínas Virais/metabolismo; Acetiltransferases/genética; Proteínas de Bactérias/genética; RNA Polimerases Dirigidas por DNA/genética; Interações Hospedeiro-Patógeno; Fagos de Pseudomonas/genética; Pseudomonas aeruginosa/genética; Transcrição Gênica; Proteínas Virais/genética

Palavras-chave

host transcriptional shutdown; phage-induced acetylation; phagehost interactions

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Pseudomonas aeruginosa / Acetiltransferases / Proteínas de Bactérias / Proteínas Virais / RNA Polimerases Dirigidas por DNA / Fagos de Pseudomonas Idioma: En Revista: Viruses Ano de publicação: 2020 Tipo de documento: Article

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