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Multiple-endpoint in vitro carcinogenicity test in human cell line TK6 distinguishes carcinogens from non-carcinogens and highlights mechanisms of action.
Chapman, Katherine E; Wilde, Eleanor C; Chapman, Fiona M; Verma, Jatin R; Shah, Ume-Kulsoom; Stannard, Leanne M; Seager, Anna L; Tonkin, James A; Brown, M Rowan; Doherty, Ann T; Johnson, George E; Doak, Shareen H; Jenkins, Gareth J S.
Afiliação
  • Chapman KE; In Vitro Toxicology Group, Institute of Life Science 1, Swansea University Medical School, Swansea University, Singleton Campus, Swansea, SA2 8PP, UK. K.E.Chapman@swansea.ac.uk.
  • Wilde EC; In Vitro Toxicology Group, Institute of Life Science 1, Swansea University Medical School, Swansea University, Singleton Campus, Swansea, SA2 8PP, UK.
  • Chapman FM; In Vitro Toxicology Group, Institute of Life Science 1, Swansea University Medical School, Swansea University, Singleton Campus, Swansea, SA2 8PP, UK.
  • Verma JR; In Vitro Toxicology Group, Institute of Life Science 1, Swansea University Medical School, Swansea University, Singleton Campus, Swansea, SA2 8PP, UK.
  • Shah UK; In Vitro Toxicology Group, Institute of Life Science 1, Swansea University Medical School, Swansea University, Singleton Campus, Swansea, SA2 8PP, UK.
  • Stannard LM; In Vitro Toxicology Group, Institute of Life Science 1, Swansea University Medical School, Swansea University, Singleton Campus, Swansea, SA2 8PP, UK.
  • Seager AL; In Vitro Toxicology Group, Institute of Life Science 1, Swansea University Medical School, Swansea University, Singleton Campus, Swansea, SA2 8PP, UK.
  • Tonkin JA; College of Engineering, Swansea University, Bay Campus, Swansea, SA1 8EN, UK.
  • Brown MR; College of Engineering, Swansea University, Bay Campus, Swansea, SA1 8EN, UK.
  • Doherty AT; Discovery Safety, AstraZeneca, DSM, Darwin Building, Cambridge Science Park, Milton Road, Cambridge, CB4 0WG, UK.
  • Johnson GE; In Vitro Toxicology Group, Institute of Life Science 1, Swansea University Medical School, Swansea University, Singleton Campus, Swansea, SA2 8PP, UK.
  • Doak SH; In Vitro Toxicology Group, Institute of Life Science 1, Swansea University Medical School, Swansea University, Singleton Campus, Swansea, SA2 8PP, UK.
  • Jenkins GJS; In Vitro Toxicology Group, Institute of Life Science 1, Swansea University Medical School, Swansea University, Singleton Campus, Swansea, SA2 8PP, UK.
Arch Toxicol ; 95(1): 321-336, 2021 01.
Article em En | MEDLINE | ID: mdl-32910239
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Projetos de Pesquisa / Carcinógenos / Testes de Carcinogenicidade / Determinação de Ponto Final Tipo de estudo: Etiology_studies / Prognostic_studies / Risk_factors_studies Limite: Humans Idioma: En Revista: Arch Toxicol Ano de publicação: 2021 Tipo de documento: Article
Texto completo
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Projetos de Pesquisa / Carcinógenos / Testes de Carcinogenicidade / Determinação de Ponto Final Tipo de estudo: Etiology_studies / Prognostic_studies / Risk_factors_studies Limite: Humans Idioma: En Revista: Arch Toxicol Ano de publicação: 2021 Tipo de documento: Article