mTOR regulates skeletogenesis through canonical and noncanonical pathways.

Tokumura, Kazuya; Iwahashi, Sayuki; Park, Gyujin; Ochiai, Shinsuke; Okayama, Yasuka; Fusawa, Hiroki; Fukasawa, Kazuya; Iezaki, Takashi; Hinoi, Eiichi

Tokumura, Kazuya; Iwahashi, Sayuki; Park, Gyujin; Ochiai, Shinsuke; Okayama, Yasuka; Fusawa, Hiroki; Fukasawa, Kazuya; Iezaki, Takashi; Hinoi, Eiichi.

Afiliação

Tokumura K; Laboratory of Pharmacology, Department of Bioactive Molecules, Gifu Pharmaceutical University, Gifu, Japan.
Iwahashi S; Laboratory of Pharmacology, Department of Bioactive Molecules, Gifu Pharmaceutical University, Gifu, Japan.
Park G; Laboratory of Pharmacology, Department of Bioactive Molecules, Gifu Pharmaceutical University, Gifu, Japan.
Ochiai S; Laboratory of Pharmacology, Department of Bioactive Molecules, Gifu Pharmaceutical University, Gifu, Japan.
Okayama Y; Laboratory of Pharmacology, Department of Bioactive Molecules, Gifu Pharmaceutical University, Gifu, Japan.
Fusawa H; Laboratory of Pharmacology, Department of Bioactive Molecules, Gifu Pharmaceutical University, Gifu, Japan.
Fukasawa K; Laboratory of Pharmacology, Department of Bioactive Molecules, Gifu Pharmaceutical University, Gifu, Japan.
Iezaki T; Laboratory of Pharmacology, Department of Bioactive Molecules, Gifu Pharmaceutical University, Gifu, Japan.
Hinoi E; Laboratory of Pharmacology, Department of Bioactive Molecules, Gifu Pharmaceutical University, Gifu, Japan; United Graduate School of Drug Discovery and Medical Information Sciences, Gifu University, Gifu, Japan. Electronic address: hinoi-e@gifu-pu.ac.jp.

Biochem Biophys Res Commun ; 533(1): 30-35, 2020 11 26.

Article em En | MEDLINE | ID: mdl-32917361

Assuntos

Condrócitos/citologia; Células-Tronco Mesenquimais/citologia; Esqueleto/embriologia; Serina-Treonina Quinases TOR/metabolismo; Animais; Condrócitos/metabolismo; Deleção de Genes; Regulação da Expressão Gênica no Desenvolvimento; Células-Tronco Mesenquimais/metabolismo; Camundongos; Transdução de Sinais; Esqueleto/metabolismo; Serina-Treonina Quinases TOR/genética

Palavras-chave

Canonical pathway; Chondrocytes; Mesenchymal cells; Noncanonical pathway; Skeletogenesis; mTOR

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Esqueleto / Condrócitos / Serina-Treonina Quinases TOR / Células-Tronco Mesenquimais Limite: Animals Idioma: En Revista: Biochem Biophys Res Commun Ano de publicação: 2020 Tipo de documento: Article

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