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Fungal mycotoxin penisuloxazin A, a novel C-terminal Hsp90 inhibitor and characteristics of its analogues on Hsp90 function related to binding sites.
Dai, Jiajia; Zhu, Meilin; Qi, Xin; Wang, Yanjuan; Li, Huilin; Tang, Shuai; Wang, Qiang; Chen, Ao; Liu, Ming; Gu, Qianqun; Li, Dehai; Li, Jing.
Afiliação
  • Dai J; Key Laboratory of Marine Drugs, Chinese Ministry of Education, School of Medicine and Pharmacy, Ocean University of China, Qingdao 266003, PR China.
  • Zhu M; Key Laboratory of Marine Drugs, Chinese Ministry of Education, School of Medicine and Pharmacy, Ocean University of China, Qingdao 266003, PR China.
  • Qi X; Key Laboratory of Marine Drugs, Chinese Ministry of Education, School of Medicine and Pharmacy, Ocean University of China, Qingdao 266003, PR China.
  • Wang Y; Key Laboratory of Marine Drugs, Chinese Ministry of Education, School of Medicine and Pharmacy, Ocean University of China, Qingdao 266003, PR China.
  • Li H; Department of Biological Chemistry, David Geffen School of Medicine, University of California, Los Angeles, CA 90095, USA.
  • Tang S; Division of Antitumor Pharmacology, State Key Laboratory of Drug Research, Shanghai Institute of Materia Medica, Academy of Sciences, Shanghai 201203, PR China.
  • Wang Q; College of Pharmacy, South Central University for Nationalities, Wuhan 430074, PR China.
  • Chen A; Key Laboratory of Marine Drugs, Chinese Ministry of Education, School of Medicine and Pharmacy, Ocean University of China, Qingdao 266003, PR China.
  • Liu M; Key Laboratory of Marine Drugs, Chinese Ministry of Education, School of Medicine and Pharmacy, Ocean University of China, Qingdao 266003, PR China; Laboratory for Marine Drugs and Bioproducts, Pilot National Laboratory for Marine Science and Technology, Qingdao 266237, PR China.
  • Gu Q; Key Laboratory of Marine Drugs, Chinese Ministry of Education, School of Medicine and Pharmacy, Ocean University of China, Qingdao 266003, PR China.
  • Li D; Key Laboratory of Marine Drugs, Chinese Ministry of Education, School of Medicine and Pharmacy, Ocean University of China, Qingdao 266003, PR China; Laboratory for Marine Drugs and Bioproducts, Pilot National Laboratory for Marine Science and Technology, Qingdao 266237, PR China. Electronic address:
  • Li J; Key Laboratory of Marine Drugs, Chinese Ministry of Education, School of Medicine and Pharmacy, Ocean University of China, Qingdao 266003, PR China; Laboratory for Marine Drugs and Bioproducts, Pilot National Laboratory for Marine Science and Technology, Qingdao 266237, PR China. Electronic address:
Biochem Pharmacol ; 182: 114218, 2020 12.
Article em En | MEDLINE | ID: mdl-32949584
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Produtos Biológicos / Proteínas de Choque Térmico HSP90 / Micotoxinas Tipo de estudo: Prognostic_studies Limite: Animals / Humans Idioma: En Revista: Biochem Pharmacol Ano de publicação: 2020 Tipo de documento: Article
Texto completo
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Produtos Biológicos / Proteínas de Choque Térmico HSP90 / Micotoxinas Tipo de estudo: Prognostic_studies Limite: Animals / Humans Idioma: En Revista: Biochem Pharmacol Ano de publicação: 2020 Tipo de documento: Article