Synthesis and Biological Evaluation of Novel Benodanil-Heterocyclic Carboxamide Hybrids as a Potential Succinate Dehydrogenase Inhibitors.

Yang, Jian; Zhao, Yongtian; Wan, Jun; Jiang, Mingfang; Jin, Hong; Tao, Ke; Hou, Taiping

Yang, Jian; Zhao, Yongtian; Wan, Jun; Jiang, Mingfang; Jin, Hong; Tao, Ke; Hou, Taiping.

Afiliação

Yang J; Key Laboratory of Bio-Resource and Eco-Environment of Ministry of Education, College of Life Sciences, Sichuan University, Chengdu 610064, China.
Zhao Y; Key Laboratory of Bio-Resource and Eco-Environment of Ministry of Education, College of Life Sciences, Sichuan University, Chengdu 610064, China.
Wan J; Key Laboratory of Bio-Resource and Eco-Environment of Ministry of Education, College of Life Sciences, Sichuan University, Chengdu 610064, China.
Jiang M; Key Laboratory of Bio-Resource and Eco-Environment of Ministry of Education, College of Life Sciences, Sichuan University, Chengdu 610064, China.
Jin H; Key Laboratory of Bio-Resource and Eco-Environment of Ministry of Education, College of Life Sciences, Sichuan University, Chengdu 610064, China.
Tao K; Key Laboratory of Bio-Resource and Eco-Environment of Ministry of Education, College of Life Sciences, Sichuan University, Chengdu 610064, China.
Hou T; Key Laboratory of Bio-Resource and Eco-Environment of Ministry of Education, College of Life Sciences, Sichuan University, Chengdu 610064, China.

Molecules ; 25(18)2020 Sep 18.

Article em En | MEDLINE | ID: mdl-32962104

Assuntos

Antifúngicos/síntese química; Benzamidas/química; Inibidores Enzimáticos/química; Compostos Heterocíclicos/química; Succinato Desidrogenase/antagonistas & inibidores; Amidas/química; Antifúngicos/metabolismo; Antifúngicos/farmacologia; Benzamidas/farmacologia; Sítios de Ligação; Desenho de Fármacos; Inibidores Enzimáticos/metabolismo; Inibidores Enzimáticos/farmacologia; Testes de Sensibilidade Microbiana; Simulação de Acoplamento Molecular; Rhizoctonia/efeitos dos fármacos; Rhizoctonia/isolamento & purificação; Relação Estrutura-Atividade; Succinato Desidrogenase/metabolismo

Palavras-chave

antifungal activity; benodanil-heterocyclic carboxamide hybrids; molecular docking; succinate dehydrogenase inhibitor

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Succinato Desidrogenase / Benzamidas / Inibidores Enzimáticos / Compostos Heterocíclicos / Antifúngicos Idioma: En Revista: Molecules Ano de publicação: 2020 Tipo de documento: Article

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