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Cholesterol Pathway Inhibition Induces TGF-ß Signaling to Promote Basal Differentiation in Pancreatic Cancer.
Gabitova-Cornell, Linara; Surumbayeva, Aizhan; Peri, Suraj; Franco-Barraza, Janusz; Restifo, Diana; Weitz, Nicole; Ogier, Charline; Goldman, Aaron R; Hartman, Tiffiney R; Francescone, Ralph; Tan, Yinfei; Nicolas, Emmanuelle; Shah, Neelima; Handorf, Elizabeth A; Cai, Kathy Q; O'Reilly, Alana M; Sloma, Ido; Chiaverelli, Rachel; Moffitt, Richard A; Khazak, Vladimir; Fang, Carolyn Y; Golemis, Erica A; Cukierman, Edna; Astsaturov, Igor.
Afiliação
  • Gabitova-Cornell L; Molecular Therapeutics Program, Fox Chase Cancer Center, 333 Cottman Avenue, Philadelphia, PA 19111, USA; The Marvin & Concetta Greenberg Pancreatic Cancer Institute, Fox Chase Cancer Center, Philadelphia, PA, USA.
  • Surumbayeva A; Molecular Therapeutics Program, Fox Chase Cancer Center, 333 Cottman Avenue, Philadelphia, PA 19111, USA; The Marvin & Concetta Greenberg Pancreatic Cancer Institute, Fox Chase Cancer Center, Philadelphia, PA, USA.
  • Peri S; Biostatistics and Bioinformatics Facility, Fox Chase Cancer Center, Philadelphia, PA, USA.
  • Franco-Barraza J; The Marvin & Concetta Greenberg Pancreatic Cancer Institute, Fox Chase Cancer Center, Philadelphia, PA, USA; Cancer Biology Program, Fox Chase Cancer Center, Philadelphia, PA, USA.
  • Restifo D; Molecular Therapeutics Program, Fox Chase Cancer Center, 333 Cottman Avenue, Philadelphia, PA 19111, USA; The Marvin & Concetta Greenberg Pancreatic Cancer Institute, Fox Chase Cancer Center, Philadelphia, PA, USA.
  • Weitz N; Molecular Therapeutics Program, Fox Chase Cancer Center, 333 Cottman Avenue, Philadelphia, PA 19111, USA; The Marvin & Concetta Greenberg Pancreatic Cancer Institute, Fox Chase Cancer Center, Philadelphia, PA, USA.
  • Ogier C; Molecular Therapeutics Program, Fox Chase Cancer Center, 333 Cottman Avenue, Philadelphia, PA 19111, USA; The Marvin & Concetta Greenberg Pancreatic Cancer Institute, Fox Chase Cancer Center, Philadelphia, PA, USA.
  • Goldman AR; Proteomics and Metabolomics Facility, The Wistar Institute, Philadelphia, PA, USA.
  • Hartman TR; Molecular Therapeutics Program, Fox Chase Cancer Center, 333 Cottman Avenue, Philadelphia, PA 19111, USA.
  • Francescone R; The Marvin & Concetta Greenberg Pancreatic Cancer Institute, Fox Chase Cancer Center, Philadelphia, PA, USA; Cancer Biology Program, Fox Chase Cancer Center, Philadelphia, PA, USA.
  • Tan Y; Cancer Biology Program, Fox Chase Cancer Center, Philadelphia, PA, USA.
  • Nicolas E; Molecular Therapeutics Program, Fox Chase Cancer Center, 333 Cottman Avenue, Philadelphia, PA 19111, USA.
  • Shah N; The Marvin & Concetta Greenberg Pancreatic Cancer Institute, Fox Chase Cancer Center, Philadelphia, PA, USA; Cancer Biology Program, Fox Chase Cancer Center, Philadelphia, PA, USA.
  • Handorf EA; Biostatistics and Bioinformatics Facility, Fox Chase Cancer Center, Philadelphia, PA, USA.
  • Cai KQ; Cancer Biology Program, Fox Chase Cancer Center, Philadelphia, PA, USA.
  • O'Reilly AM; Molecular Therapeutics Program, Fox Chase Cancer Center, 333 Cottman Avenue, Philadelphia, PA 19111, USA.
  • Sloma I; Champions Oncology, Inc., Hackensack, NJ, USA.
  • Chiaverelli R; Champions Oncology, Inc., Hackensack, NJ, USA.
  • Moffitt RA; Department of Biomedical Informatics, Stony Brook Cancer Center, Stony Brook, NY, USA.
  • Khazak V; NexusPharma, Inc., Philadelphia, PA, USA.
  • Fang CY; Cancer Prevention and Control Program, Fox Chase Cancer Center, Philadelphia, PA, USA.
  • Golemis EA; Molecular Therapeutics Program, Fox Chase Cancer Center, 333 Cottman Avenue, Philadelphia, PA 19111, USA.
  • Cukierman E; The Marvin & Concetta Greenberg Pancreatic Cancer Institute, Fox Chase Cancer Center, Philadelphia, PA, USA; Cancer Biology Program, Fox Chase Cancer Center, Philadelphia, PA, USA.
  • Astsaturov I; Molecular Therapeutics Program, Fox Chase Cancer Center, 333 Cottman Avenue, Philadelphia, PA 19111, USA; The Marvin & Concetta Greenberg Pancreatic Cancer Institute, Fox Chase Cancer Center, Philadelphia, PA, USA; Kazan Federal University, Kazan, Russian Federation. Electronic address: igor.ast
Cancer Cell ; 38(4): 567-583.e11, 2020 10 12.
Article em En | MEDLINE | ID: mdl-32976774
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Neoplasias Pancreáticas / Fator de Crescimento Transformador beta / Carcinoma Ductal Pancreático / Vias Biossintéticas / LDL-Colesterol Tipo de estudo: Prognostic_studies Limite: Animals / Humans Idioma: En Revista: Cancer Cell Ano de publicação: 2020 Tipo de documento: Article
Texto completo
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Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Neoplasias Pancreáticas / Fator de Crescimento Transformador beta / Carcinoma Ductal Pancreático / Vias Biossintéticas / LDL-Colesterol Tipo de estudo: Prognostic_studies Limite: Animals / Humans Idioma: En Revista: Cancer Cell Ano de publicação: 2020 Tipo de documento: Article