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Dexamethasone prodrug nanomedicine (ZSJ-0228) treatment significantly reduces lupus nephritis in mice without measurable side effects - A 5-month study.
Zhao, Zhifeng; Jia, Zhenshan; Foster, Kirk W; Wei, Xin; Qiao, Fangfang; Jiang, Haochen; Jin, Yan; Li, Guojuan; Chen, Ningrong; Zhao, Gang; Thiele, Geoffrey M; Medlin, Jennifer L; O'Dell, James R; Wang, Dong.
Afiliação
  • Zhao Z; Department of Pharmaceutical Sciences, College of Pharmacy, University of Nebraska Medical Center, Omaha, NE.
  • Jia Z; Department of Pharmaceutical Sciences, College of Pharmacy, University of Nebraska Medical Center, Omaha, NE.
  • Foster KW; Department of Pathology and Microbiology, College of Medicine, University of Nebraska Medical Center, Omaha, NE.
  • Wei X; Department of Pharmaceutical Sciences, College of Pharmacy, University of Nebraska Medical Center, Omaha, NE.
  • Qiao F; Department of Pharmaceutical Sciences, College of Pharmacy, University of Nebraska Medical Center, Omaha, NE.
  • Jiang H; Department of Pharmaceutical Sciences, College of Pharmacy, University of Nebraska Medical Center, Omaha, NE.
  • Jin Y; Department of Pharmaceutical Sciences, College of Pharmacy, University of Nebraska Medical Center, Omaha, NE.
  • Li G; Department of Pharmaceutical Sciences, College of Pharmacy, University of Nebraska Medical Center, Omaha, NE.
  • Chen N; Department of Pharmaceutical Sciences, College of Pharmacy, University of Nebraska Medical Center, Omaha, NE.
  • Zhao G; Department of Pharmaceutical Sciences, College of Pharmacy, University of Nebraska Medical Center, Omaha, NE.
  • Thiele GM; Division of Rheumatology and Immunology, Department of Internal Medicine, College of Medicine, University of Nebraska Medical Center, Omaha, NE; Veterans Affairs Nebraska-Western Iowa Health Care System, Omaha, NE, USA.
  • Medlin JL; Division of Rheumatology and Immunology, Department of Internal Medicine, College of Medicine, University of Nebraska Medical Center, Omaha, NE.
  • O'Dell JR; Division of Rheumatology and Immunology, Department of Internal Medicine, College of Medicine, University of Nebraska Medical Center, Omaha, NE; Veterans Affairs Nebraska-Western Iowa Health Care System, Omaha, NE, USA.
  • Wang D; Department of Pharmaceutical Sciences, College of Pharmacy, University of Nebraska Medical Center, Omaha, NE. Electronic address: dwang@unmc.edu.
Nanomedicine ; 31: 102302, 2021 01.
Article em En | MEDLINE | ID: mdl-32980548
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Texto completo: 1 Coleções: 01-internacional Contexto em Saúde: 6_ODS3_enfermedades_notrasmisibles Base de dados: MEDLINE Assunto principal: Nefrite Lúpica / Nanomedicina Tipo de estudo: Incidence_studies / Prognostic_studies Limite: Animals Idioma: En Revista: Nanomedicine Ano de publicação: 2021 Tipo de documento: Article
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Texto completo: 1 Coleções: 01-internacional Contexto em Saúde: 6_ODS3_enfermedades_notrasmisibles Base de dados: MEDLINE Assunto principal: Nefrite Lúpica / Nanomedicina Tipo de estudo: Incidence_studies / Prognostic_studies Limite: Animals Idioma: En Revista: Nanomedicine Ano de publicação: 2021 Tipo de documento: Article