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Brain immune cells undergo cGAS/STING-dependent apoptosis during herpes simplex virus type 1 infection to limit type I IFN production.
Reinert, Line S; Rashidi, Ahmad S; Tran, Diana N; Katzilieris-Petras, Georgios; Hvidt, Astrid K; Gohr, Mette; Fruhwürth, Stefanie; Bodda, Chiranjeevi; Thomsen, Martin K; Vendelbo, Mikkel H; Khan, Ahmad R; Hansen, Brian; Bergström, Petra; Agholme, Lotta; Mogensen, Trine H; Christensen, Maria H; Nyengaard, Jens R; Sen, Ganes C; Zetterberg, Henrik; Verjans, Georges Mgm; Paludan, Søren R.
Afiliação
  • Reinert LS; Department of Biomedicine, Aarhus University, Aarhus, Denmark.
  • Rashidi AS; Department of Biomedicine, Aarhus University, Aarhus, Denmark.
  • Tran DN; Department of Viroscience, Erasmus Medical Centre, Rotterdam, Netherlands.
  • Katzilieris-Petras G; Department of Viroscience, Erasmus Medical Centre, Rotterdam, Netherlands.
  • Hvidt AK; Department of Biomedicine, Aarhus University, Aarhus, Denmark.
  • Gohr M; Department of Biomedicine, Aarhus University, Aarhus, Denmark.
  • Fruhwürth S; Department of Biomedicine, Aarhus University, Aarhus, Denmark.
  • Bodda C; Department of Psychiatry and Neurochemistry, Institute of Neuroscience and Physiology, Sahlgrenska Academy at the University of Gothenburg, Sweden.
  • Thomsen MK; Department of Biomedicine, Aarhus University, Aarhus, Denmark.
  • Vendelbo MH; Department of Biomedicine, Aarhus University, Aarhus, Denmark.
  • Khan AR; Department of Biomedicine, Aarhus University, Aarhus, Denmark.
  • Hansen B; Department of Nuclear Medicine & PET Centre, Aarhus University Hospital, Denmark.
  • Bergström P; Center of Functionally Integrative Neuroscience, Aarhus University, Aarhus, Denmark.
  • Agholme L; Centre of Biomedical Research, SGPGI Campus, Lucknow, India.
  • Mogensen TH; Center of Functionally Integrative Neuroscience, Aarhus University, Aarhus, Denmark.
  • Christensen MH; Institute of Neuroscience and Physiology, Department of Psychiatry and Neurochemistry, Sahlgrenska Academy at the University of Gothenburg, Gothenburg, Germany.
  • Nyengaard JR; Institute of Neuroscience and Physiology, Department of Psychiatry and Neurochemistry, Sahlgrenska Academy at the University of Gothenburg, Gothenburg, Germany.
  • Sen GC; Department of Biomedicine, Aarhus University, Aarhus, Denmark.
  • Zetterberg H; Institute of Innate Immunity, University of Bonn, Bonn, Germany.
  • Verjans GM; Department of Clinical Medicine, University of Aarhus, Aarhus, Denmark.
  • Paludan SR; Department of Immunology, Lerner Research Institute, Cleveland Clinic, Cleveland, Ohio, USA.
J Clin Invest ; 131(1)2021 01 04.
Article em En | MEDLINE | ID: mdl-32990676

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Encéfalo / Interferon Tipo I / Herpesvirus Humano 1 / Herpes Simples / Proteínas de Membrana / Nucleotidiltransferases Limite: Animals / Humans / Male Idioma: En Revista: J Clin Invest Ano de publicação: 2021 Tipo de documento: Article

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Encéfalo / Interferon Tipo I / Herpesvirus Humano 1 / Herpes Simples / Proteínas de Membrana / Nucleotidiltransferases Limite: Animals / Humans / Male Idioma: En Revista: J Clin Invest Ano de publicação: 2021 Tipo de documento: Article