Evolutionary History of Alzheimer Disease-Causing Protein Family Presenilins with Pathological Implications.

Khan, Ammad Aslam; Ali, Raja Hashim; Mirza, Bushra

Khan, Ammad Aslam; Ali, Raja Hashim; Mirza, Bushra.

Afiliação

Khan AA; Department of Bioinformatics and Computational Biology, Virtual University, Lahore, 547 92, Pakistan. ammadaslamkhan@gmail.com.
Ali RH; Department of Biochemistry, Barrett Hodgson University, Korangi Creek, Karachi, 749 00, Pakistan. ammadaslamkhan@gmail.com.
Mirza B; Machine Intelligence Group (MInG Lab), Faculty of Computer Science And Engg., Ghulam Ishaq Khan Institute of Engg. Sciences and Technology, Topi, 236 40, Pakistan.

J Mol Evol ; 88(8-9): 674-688, 2020 11.

Article em En | MEDLINE | ID: mdl-33001284

Assuntos

Doença de Alzheimer; Evolução Molecular; Presenilinas/genética; Secretases da Proteína Precursora do Amiloide/genética; Dictyostelium; Humanos

Palavras-chave

Alzheimer disease; Amyloid-beta; Endoproteolysis; Presenilin; Protein evolution; Î³-Secretase

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Evolução Molecular / Presenilinas / Doença de Alzheimer Limite: Humans Idioma: En Revista: J Mol Evol Ano de publicação: 2020 Tipo de documento: Article

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