West Nile virus encephalitis: A report of two cases and review of neuroradiological features.
Radiol Case Rep
; 15(11): 2422-2426, 2020 Nov.
Article
em En
| MEDLINE
| ID: mdl-33005280
ABSTRACT
West Nile virus (WNV) is a single-stranded RNA arbovirus of Flavivirus genus that is endemic to the United States and known to cause neuroinvasive disease. Diagnosis is confirmed by the presence of WNV-specific IgM antibodies within serum or cerebrospinal fluid (CSF). Radiologically, it presents as hyperintense T2 signal within deep brain structures (ie, thalami and mid-brain) with or without cerebral peduncle and substantia nigra involvement. On diffusion-weighted imaging, restricted diffusion is reported in basal ganglia and disseminated throughout the white matter. In this report, we describe the imaging findings for 2 cases of WNV from our institution; a 56-year-old female and a 34-year-old female. Increased vigilance for WNV is warranted, particularly in immunosuppressed patients presenting with a clinical picture of viral meningoencephalitis despite initial negative magnetic resonance imaging or CSF analysis. A high suspicion for WNV disease should prompt repeat imaging or laboratory workup.
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Coleções:
01-internacional
Base de dados:
MEDLINE
Idioma:
En
Revista:
Radiol Case Rep
Ano de publicação:
2020
Tipo de documento:
Article