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Format chain exchange (FORCE) for high-throughput generation of bispecific antibodies in combinatorial binder-format matrices.
Dengl, Stefan; Mayer, Klaus; Bormann, Felix; Duerr, Harald; Hoffmann, Eike; Nussbaum, Bianca; Tischler, Michael; Wagner, Martina; Kuglstatter, Andreas; Leibrock, Lea; Buldun, Can; Georges, Guy; Brinkmann, Ulrich.
Afiliação
  • Dengl S; Roche Pharma Research and Early Development (pRED), Large Molecule Research, Roche Innovation Center Munich, Penzberg, Germany.
  • Mayer K; Roche Pharma Research and Early Development (pRED), Large Molecule Research, Roche Innovation Center Munich, Penzberg, Germany.
  • Bormann F; Roche Pharma Research and Early Development (pRED), Large Molecule Research, Roche Innovation Center Munich, Penzberg, Germany.
  • Duerr H; Roche Pharma Research and Early Development (pRED), Large Molecule Research, Roche Innovation Center Munich, Penzberg, Germany.
  • Hoffmann E; Roche Pharma Research and Early Development (pRED), Large Molecule Research, Roche Innovation Center Munich, Penzberg, Germany.
  • Nussbaum B; Roche Pharma Research and Early Development (pRED), Large Molecule Research, Roche Innovation Center Munich, Penzberg, Germany.
  • Tischler M; Roche Pharma Research and Early Development (pRED), Large Molecule Research, Roche Innovation Center Munich, Penzberg, Germany.
  • Wagner M; Roche Pharma Research and Early Development (pRED), Large Molecule Research, Roche Innovation Center Munich, Penzberg, Germany.
  • Kuglstatter A; Roche Pharma Research and Early Development (pRED), Structural Biology, Roche Innovation Center Basel, Basel, Switzerland.
  • Leibrock L; Roche Pharma Research and Early Development (pRED), Structural Biology, Roche Innovation Center Basel, Basel, Switzerland.
  • Buldun C; Roche Pharma Research and Early Development (pRED), Large Molecule Research, Roche Innovation Center Munich, Penzberg, Germany.
  • Georges G; Roche Pharma Research and Early Development (pRED), Large Molecule Research, Roche Innovation Center Munich, Penzberg, Germany.
  • Brinkmann U; Roche Pharma Research and Early Development (pRED), Large Molecule Research, Roche Innovation Center Munich, Penzberg, Germany. ulrich.brinkmann@roche.com.
Nat Commun ; 11(1): 4974, 2020 10 02.
Article em En | MEDLINE | ID: mdl-33009381
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Anticorpos Biespecíficos / Ensaios de Triagem em Larga Escala Limite: Humans Idioma: En Revista: Nat Commun Ano de publicação: 2020 Tipo de documento: Article
Texto completo
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Anticorpos Biespecíficos / Ensaios de Triagem em Larga Escala Limite: Humans Idioma: En Revista: Nat Commun Ano de publicação: 2020 Tipo de documento: Article