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Epigenetic modulator inhibition overcomes temozolomide chemoresistance and antagonizes tumor recurrence of glioblastoma.
Moon, Byoung-San; Cai, Mingyang; Lee, Grace; Zhao, Tong; Song, Xiaofeng; Giannotta, Steven L; Attenello, Frank J; Yu, Min; Lu, Wange.
Afiliação
  • Moon BS; Department of Neurosurgery and.
  • Cai M; Broad Center for Regenerative Medicine and Stem Cell Research, Keck Department of Stem Cell Biology and Regenerative Medicine, Keck School of Medicine, University of Southern California, Los Angeles, California, USA.
  • Lee G; Therapeutics and Biotechnology Division, Drug Discovery Platform Research Center, Korea Research Institute of Chemical Technology (KRICT), Daejeon, Korea.
  • Zhao T; Department of Biotechnology, Chonnam National University, Yeosu, Korea.
  • Song X; Broad Center for Regenerative Medicine and Stem Cell Research, Keck Department of Stem Cell Biology and Regenerative Medicine, Keck School of Medicine, University of Southern California, Los Angeles, California, USA.
  • Giannotta SL; Broad Center for Regenerative Medicine and Stem Cell Research, Keck Department of Stem Cell Biology and Regenerative Medicine, Keck School of Medicine, University of Southern California, Los Angeles, California, USA.
  • Attenello FJ; State Key Laboratory of Medicinal Chemical Biology and College of Life Sciences, Nankai University, Tianjin, China.
  • Yu M; Department of Biomedical Engineering, Nanjing University of Aeronautics and Astronautics, Nanjing, China.
  • Lu W; Department of Neurosurgery and.
J Clin Invest ; 130(11): 5782-5799, 2020 11 02.
Article em En | MEDLINE | ID: mdl-33016927
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Texto completo: 1 Coleções: 01-internacional Contexto em Saúde: 6_ODS3_enfermedades_notrasmisibles Base de dados: MEDLINE Assunto principal: Neoplasias Encefálicas / DNA de Neoplasias / Regulação Neoplásica da Expressão Gênica / Glioblastoma / Resistencia a Medicamentos Antineoplásicos / Metilação de DNA / Epigênese Genética / Temozolomida Tipo de estudo: Prognostic_studies Limite: Animals / Humans Idioma: En Revista: J Clin Invest Ano de publicação: 2020 Tipo de documento: Article
Texto completo
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Texto completo: 1 Coleções: 01-internacional Contexto em Saúde: 6_ODS3_enfermedades_notrasmisibles Base de dados: MEDLINE Assunto principal: Neoplasias Encefálicas / DNA de Neoplasias / Regulação Neoplásica da Expressão Gênica / Glioblastoma / Resistencia a Medicamentos Antineoplásicos / Metilação de DNA / Epigênese Genética / Temozolomida Tipo de estudo: Prognostic_studies Limite: Animals / Humans Idioma: En Revista: J Clin Invest Ano de publicação: 2020 Tipo de documento: Article