Steroid sulphatase levels are higher in males than in females of the root vole (Microtus oeconomus). Yet another rodent with an active Y-linked allele?
Hum Genet
; 77(1): 6-11, 1987 Sep.
Article
em En
| MEDLINE
| ID: mdl-3305308
ABSTRACT
Steroid sulfatase (STS; EC 3.1.6.2) levels were assayed in cultured fibroblasts of root voles captured in the wild. Four independent experiments were performed using two different substrates (DHEAS and E1S). Evidence is presented that in this species, STS levels are significantly higher in males than in females (ratio 1.61). We discuss our findings on a comparative basis and suggest that in the root vole the STS gene(s) is X- and Y-linked (as in the mouse) and that it is subject to X-inactivation, or partially so, on one of the X chromosomes in the female.
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Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Sulfatases
/
Cromossomo Y
/
Arvicolinae
/
Ligação Genética
Limite:
Animals
Idioma:
En
Revista:
Hum Genet
Ano de publicação:
1987
Tipo de documento:
Article