Epidemiology of Kawasaki Disease in South Korea: A Nationwide Survey 2015-2017.
Pediatr Infect Dis J
; 39(11): 1012-1016, 2020 11.
Article
em En
| MEDLINE
| ID: mdl-33075217
ABSTRACT
BACKGROUND:
This study aimed to investigate recent epidemiologic features of Kawasaki disease (KD) in South Korea.METHODS:
The ninth triennial nationwide questionnaire survey collected data on the demographic findings, symptoms and signs, treatment patterns and coronary artery complications of acute-phase KD occurred in 2015-2017 from 98 hospitals with pediatric residency programs and 108 community hospitals without residency programs.RESULTS:
We received data from 93 of the 98 hospitals (response rate 94.9%) with residency programs and 75 of the 108 community-based children's hospitals (response rate 69.4%) without residency programs. In the 3-year survey period, a total of 15,378 (5449 in 2015, 5171 in 2016 and 4758 in 2017) cases of KD were reported. The mean age at diagnosis was 33.0 ± 24.8 months (range 0-205 months), and the male-to-female ratio was 1.411. The overall KD incidence was 196.9 (202.2 in 2015, 197.1 in 2016 and 191.0 in 2017) per 100,000 younger than 5 years population. Recurrent cases were 4.85%. KD occurred more frequently during winter (December-January) and late spring (May-June). Intravenous immunoglobulin (IVIG) was administered to 95% of the patients; nonresponder rate for the first IVIG was 14.8%. Coronary artery aneurysms and giant coronary artery aneurysms (internal diameter >8 mm) occurred in 1.7% and 19 patients, respectively. Two patients died due to multiorgan failure and hepatic encephalopathy.CONCLUSION:
Peak incidence of KD in South Korea was 202.2 per 100,000 younger than 5 years population (2015), and the incidence of giant coronary artery aneurysm decreased to 0.09% (2017).
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Síndrome de Linfonodos Mucocutâneos
Tipo de estudo:
Etiology_studies
/
Incidence_studies
/
Prognostic_studies
/
Screening_studies
Limite:
Adolescent
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Child
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Child, preschool
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Female
/
Humans
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Infant
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Male
/
Newborn
País/Região como assunto:
Asia
Idioma:
En
Revista:
Pediatr Infect Dis J
Ano de publicação:
2020
Tipo de documento:
Article