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Proximal colon-derived O-glycosylated mucus encapsulates and modulates the microbiota.
Bergstrom, Kirk; Shan, Xindi; Casero, David; Batushansky, Albert; Lagishetty, Venu; Jacobs, Jonathan P; Hoover, Christopher; Kondo, Yuji; Shao, Bojing; Gao, Liang; Zandberg, Wesley; Noyovitz, Benjamin; McDaniel, J Michael; Gibson, Deanna L; Pakpour, Sepideh; Kazemian, Negin; McGee, Samuel; Houchen, Courtney W; Rao, Chinthalapally V; Griffin, Timothy M; Sonnenburg, Justin L; McEver, Rodger P; Braun, Jonathan; Xia, Lijun.
Afiliação
  • Bergstrom K; Cardiovascular Biology Research Program, Oklahoma Medical Research Foundation, Oklahoma City, OK 73104, USA. lijun-xia@omrf.org kirk.bergstrom@ubc.ca.
  • Shan X; Department of Biology, University of British Columbia, Okanagan Campus, Kelowna, British Columbia V1V 1V7, Canada.
  • Casero D; Cardiovascular Biology Research Program, Oklahoma Medical Research Foundation, Oklahoma City, OK 73104, USA.
  • Batushansky A; Inflammatory Bowel and Immunobiology Institute, Cedars Sinai Medical Center, Los Angeles, CA 90048, USA.
  • Lagishetty V; Aging and Metabolism Research Program, Oklahoma Medical Research Foundation, Oklahoma City, OK 73104, USA.
  • Jacobs JP; Vatche and Tamar Manoukian Division of Digestive Diseases, Department of Medicine, David Geffen School of Medicine at UCLA, Los Angeles, CA 90095, USA.
  • Hoover C; Division of Gastroenterology, Hepatology and Parenteral Nutrition, VA Greater Los Angeles Healthcare System, Los Angeles, CA 90025, USA.
  • Kondo Y; Cardiovascular Biology Research Program, Oklahoma Medical Research Foundation, Oklahoma City, OK 73104, USA.
  • Shao B; Cardiovascular Biology Research Program, Oklahoma Medical Research Foundation, Oklahoma City, OK 73104, USA.
  • Gao L; Cardiovascular Biology Research Program, Oklahoma Medical Research Foundation, Oklahoma City, OK 73104, USA.
  • Zandberg W; Cardiovascular Biology Research Program, Oklahoma Medical Research Foundation, Oklahoma City, OK 73104, USA.
  • Noyovitz B; Department of Chemistry, University of British Columbia, Okanagan Campus, Kelowna, British Columbia V1V 1V7, Canada.
  • McDaniel JM; Department of Chemistry, University of British Columbia, Okanagan Campus, Kelowna, British Columbia V1V 1V7, Canada.
  • Gibson DL; Cardiovascular Biology Research Program, Oklahoma Medical Research Foundation, Oklahoma City, OK 73104, USA.
  • Pakpour S; Department of Biology, University of British Columbia, Okanagan Campus, Kelowna, British Columbia V1V 1V7, Canada.
  • Kazemian N; School of Engineering, University of British Columbia, Okanagan Campus, Kelowna, British Columbia V1V 1V7, Canada.
  • McGee S; School of Engineering, University of British Columbia, Okanagan Campus, Kelowna, British Columbia V1V 1V7, Canada.
  • Houchen CW; Cardiovascular Biology Research Program, Oklahoma Medical Research Foundation, Oklahoma City, OK 73104, USA.
  • Rao CV; Department of Internal Medicine, University of Oklahoma Health Sciences Center, Oklahoma City, OK 73104, USA.
  • Griffin TM; Department of Internal Medicine, University of Oklahoma Health Sciences Center, Oklahoma City, OK 73104, USA.
  • Sonnenburg JL; Aging and Metabolism Research Program, Oklahoma Medical Research Foundation, Oklahoma City, OK 73104, USA.
  • McEver RP; Department of Biochemistry and Molecular Biology, University of Oklahoma Health Sciences Center, Oklahoma City, OK 73104, USA.
  • Braun J; Department of Microbiology and Immunology, Stanford University School of Medicine, Stanford, CA 94305, USA.
  • Xia L; Cardiovascular Biology Research Program, Oklahoma Medical Research Foundation, Oklahoma City, OK 73104, USA.
Science ; 370(6515): 467-472, 2020 10 23.
Article em En | MEDLINE | ID: mdl-33093110
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Texto completo: 1 Coleções: 01-internacional Contexto em Saúde: 3_ND Base de dados: MEDLINE Assunto principal: Colo / Mucina-2 / Microbioma Gastrointestinal / Muco Limite: Animals Idioma: En Revista: Science Ano de publicação: 2020 Tipo de documento: Article
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Contexto em Saúde: 3_ND Base de dados: MEDLINE Assunto principal: Colo / Mucina-2 / Microbioma Gastrointestinal / Muco Limite: Animals Idioma: En Revista: Science Ano de publicação: 2020 Tipo de documento: Article