Adverse pathophysiological influence of early testosterone therapy on the testes of boys with higher grade sex chromosome aneuploidies (HGAs): a retrospective, cross-sectional study.

Spaziani, M; Tarantino, C; Pozza, C; Anzuini, A; Panimolle, F; Papi, G; Gianfrilli, D; Lenzi, A; Radicioni, A F

Spaziani, M; Tarantino, C; Pozza, C; Anzuini, A; Panimolle, F; Papi, G; Gianfrilli, D; Lenzi, A; Radicioni, A F.

Afiliação

Spaziani M; Section of Medical Pathophysiology and Endocrinology, Department of Experimental Medicine, Sapienza University of Rome, 00161, Rome, Italy. matteo.spaziani@uniroma1.it.
Tarantino C; Centre for Rare Diseases, Policlinico Umberto I, Rome, Italy. matteo.spaziani@uniroma1.it.
Pozza C; Section of Medical Pathophysiology and Endocrinology, Department of Experimental Medicine, Sapienza University of Rome, 00161, Rome, Italy.
Anzuini A; Centre for Rare Diseases, Policlinico Umberto I, Rome, Italy.
Panimolle F; Section of Medical Pathophysiology and Endocrinology, Department of Experimental Medicine, Sapienza University of Rome, 00161, Rome, Italy.
Papi G; Section of Medical Pathophysiology and Endocrinology, Department of Experimental Medicine, Sapienza University of Rome, 00161, Rome, Italy.
Gianfrilli D; Centre for Rare Diseases, Policlinico Umberto I, Rome, Italy.
Lenzi A; Section of Medical Pathophysiology and Endocrinology, Department of Experimental Medicine, Sapienza University of Rome, 00161, Rome, Italy.
Radicioni AF; Section of Medical Pathophysiology and Endocrinology, Department of Experimental Medicine, Sapienza University of Rome, 00161, Rome, Italy.

J Endocrinol Invest ; 44(7): 1483-1490, 2021 Jul.

Article em En | MEDLINE | ID: mdl-33098655

Assuntos

Aneuploidia; Gonadotropina Coriônica/administração & dosagem; Cromossomos Sexuais/genética; Testículo/fisiopatologia; Testosterona/administração & dosagem; Hormônio Antimülleriano/sangue; Criança; Gonadotropina Coriônica/sangue; Estudos Transversais; Hormônio Foliculoestimulante/sangue; Seguimentos; Humanos; Inibinas/sangue; Hormônio Luteinizante/sangue; Masculino; Prognóstico; Estudos Retrospectivos; Testículo/efeitos dos fármacos; Testículo/metabolismo; Testosterona/sangue

Palavras-chave

48,XXXY; 48,XXYY; 49,XXXXY; Cryptorchidism; Leydig cells; Sertoli cells

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Cromossomos Sexuais / Testículo / Testosterona / Gonadotropina Coriônica / Aneuploidia Tipo de estudo: Observational_studies / Prevalence_studies / Prognostic_studies / Risk_factors_studies Limite: Child / Humans / Male Idioma: En Revista: J Endocrinol Invest Ano de publicação: 2021 Tipo de documento: Article

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