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New chalcone-tethered 1,3,5-triazines potentiate the anticancer effect of cisplatin against human lung adenocarcinoma A549 cells by enhancing DNA damage and cell apoptosis.
El-Wakil, Marwa H; Khattab, Sherine N; El-Yazbi, Amira F; El-Nikhely, Nefertiti; Soffar, Ahmed; Khalil, Hosam H.
Afiliação
  • El-Wakil MH; Department of Pharmaceutical Chemistry, Faculty of Pharmacy, Alexandria University, Alexandria 21521, Egypt.
  • Khattab SN; Department of Chemistry, Faculty of Science, Alexandria University, Alexandria 21321, Egypt; Cancer Nanotechnology Research Laboratory (CNRL), Faculty of Pharmacy, Alexandria University, Alexandria 21521, Egypt. Electronic address: sh.n.khattab@gmail.com.
  • El-Yazbi AF; Department of Pharmaceutical Analytical Chemistry, Faculty of Pharmacy, Alexandria University, Alexandria 21521, Egypt.
  • El-Nikhely N; Department of Biotechnology, Institute of Graduate Studies and Research, Alexandria University, Alexandria 21526, Egypt.
  • Soffar A; Department of Zoology, Faculty of Science, Alexandria University, Alexandria 21321, Egypt.
  • Khalil HH; Department of Chemistry, Faculty of Science, Alexandria University, Alexandria 21321, Egypt.
Bioorg Chem ; 105: 104393, 2020 12.
Article em En | MEDLINE | ID: mdl-33120322
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Triazinas / DNA / Chalcona / Cisplatino / Apoptose / Antineoplásicos Limite: Animals / Humans Idioma: En Revista: Bioorg Chem Ano de publicação: 2020 Tipo de documento: Article
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Triazinas / DNA / Chalcona / Cisplatino / Apoptose / Antineoplásicos Limite: Animals / Humans Idioma: En Revista: Bioorg Chem Ano de publicação: 2020 Tipo de documento: Article