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Upregulation of Antioxidant Capacity and Nucleotide Precursor Availability Suffices for Oncogenic Transformation.
Zhang, Yang; Xu, Yi; Lu, Wenyun; Ghergurovich, Jonathan M; Guo, Lili; Blair, Ian A; Rabinowitz, Joshua D; Yang, Xiaolu.
Afiliação
  • Zhang Y; Department of Cancer Biology and Abramson Family Cancer Research Institute, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA.
  • Xu Y; Department of Cancer Biology and Abramson Family Cancer Research Institute, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA.
  • Lu W; Lewis-Sigler Institute for Integrative Genomics, Princeton University, Princeton, NJ 08540, USA; Department of Chemistry, Princeton University, Princeton, NJ 08540, USA.
  • Ghergurovich JM; Lewis-Sigler Institute for Integrative Genomics, Princeton University, Princeton, NJ 08540, USA; Department of Molecular Biology, Princeton University, Princeton, NJ 08540, USA.
  • Guo L; Department of Systems Pharmacology and Translational Therapeutics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA.
  • Blair IA; Department of Systems Pharmacology and Translational Therapeutics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA.
  • Rabinowitz JD; Lewis-Sigler Institute for Integrative Genomics, Princeton University, Princeton, NJ 08540, USA; Department of Chemistry, Princeton University, Princeton, NJ 08540, USA.
  • Yang X; Department of Cancer Biology and Abramson Family Cancer Research Institute, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA. Electronic address: xyang@pennmedicine.upenn.edu.
Cell Metab ; 33(1): 94-109.e8, 2021 01 05.
Article em En | MEDLINE | ID: mdl-33159852
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Regulação para Cima / Transformação Celular Neoplásica / Glucosefosfato Desidrogenase / Antioxidantes / Nucleotídeos Limite: Animals / Humans / Male Idioma: En Revista: Cell Metab Ano de publicação: 2021 Tipo de documento: Article
Texto completo
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Regulação para Cima / Transformação Celular Neoplásica / Glucosefosfato Desidrogenase / Antioxidantes / Nucleotídeos Limite: Animals / Humans / Male Idioma: En Revista: Cell Metab Ano de publicação: 2021 Tipo de documento: Article