Neutralising effects of small molecule toxin inhibitors on nanofractionated coagulopathic Crotalinae snake venoms.
Acta Pharm Sin B
; 10(10): 1835-1845, 2020 Oct.
Article
em En
| MEDLINE
| ID: mdl-33163338
ACN, acetonitrile; Antivenom; CTL, C-type lectins; Chelators; DMSO, dimethyl sulfoxide; Dimercaprol; FA, formic acid; HTS, high-throughput screening; LC, liquid chromatography; MS, mass spectrometry; Marimastat; NOI, no observed inhibition; Nanofractionation; PBS, phosphate buffered saline; PLA2, phospholipase A2; PN, partly neutralised at 20 µmol/L inhibitor concentrations; SVMP, snake venom metalloproteinase; SVSP, snake venom serine protease; Snakebite; TIC, total ion current; Varespladib; WHO, World Health Organization; XIC, extracted ion current
Texto completo:
1
Coleções:
01-internacional
Contexto em Saúde:
2_ODS3
Base de dados:
MEDLINE
Idioma:
En
Revista:
Acta Pharm Sin B
Ano de publicação:
2020
Tipo de documento:
Article