Epithelial Transfer of the Tyrosine Kinase Inhibitors Erlotinib, Gefitinib, Afatinib, Crizotinib, Sorafenib, Sunitinib, and Dasatinib: Implications for Clinical Resistance.

Honeywell, Richard J; Kathmann, Ietje; Giovannetti, Elisa; Tibaldi, Carmelo; Smit, Egbert F; Rovithi, Maria N; Verheul, Henk M W; Peters, Godefridus J

Honeywell, Richard J; Kathmann, Ietje; Giovannetti, Elisa; Tibaldi, Carmelo; Smit, Egbert F; Rovithi, Maria N; Verheul, Henk M W; Peters, Godefridus J.

Afiliação

Honeywell RJ; Department of Medical Oncology, Amsterdam UMC, VU University Medical Center, PO Box 7057, 1007 MB Amsterdam, The Netherlands.
Kathmann I; Department of Pharmacy, Amsterdam UMC, VU University Medical Center, PO Box 7057, 1007 MB Amsterdam, The Netherlands.
Giovannetti E; Department of Medical Oncology, Amsterdam UMC, VU University Medical Center, PO Box 7057, 1007 MB Amsterdam, The Netherlands.
Tibaldi C; Department of Medical Oncology, Amsterdam UMC, VU University Medical Center, PO Box 7057, 1007 MB Amsterdam, The Netherlands.
Smit EF; Cancer Pharmacology Lab, AIRC Start-Up Unit, Fondazione Pisana per la Scienza, 56017 Pisa, Italy.
Rovithi MN; Division of Oncology, Department of Oncology, S. Luca Hospital, 55100 Lucca, Italy.
Verheul HMW; Department of Thoracic Oncology, Netherlands Cancer Institute, 1066 CX Amsterdam, The Netherlands.
Peters GJ; Department of Medical Oncology, Amsterdam UMC, VU University Medical Center, PO Box 7057, 1007 MB Amsterdam, The Netherlands.

Cancers (Basel) ; 12(11)2020 Nov 10.

Article em En | MEDLINE | ID: mdl-33182766

Palavras-chave

CaCo2 model system; efflux ratio; gut-epithelial transfer; red blood cell accumulation; tyrosine kinase inhibitors

Texto completo

Imprimir

XML

PubMed Links

Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Tipo de estudo: Prognostic_studies Idioma: En Revista: Cancers (Basel) Ano de publicação: 2020 Tipo de documento: Article

Texto completo

Imprimir

XML

PubMed Links

Buscar no Google