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Discovery and SAR of Novel Disubstituted Quinazolines as Dual PI3Kalpha/mTOR Inhibitors Targeting Breast Cancer.
Al-Ashmawy, Aisha A K; Elokely, Khaled M; Perez-Leal, Oscar; Rico, Mario; Gordon, John; Mateo, George; Omar, Abdelsattar M; Abou-Gharbia, Magid; Childers, Wayne E.
Afiliação
  • Al-Ashmawy AAK; Moulder Center for Drug Discovery Research, Temple University, School of Pharmacy, 3307 N. Broad Street, Philadelphia, Pennsylvania 19140, United States.
  • Elokely KM; Department of Therapeutic Chemistry, Pharmaceutical and Drug Industries Research Division, National Research Center, Dokki, Cairo 12622, Egypt.
  • Perez-Leal O; Moulder Center for Drug Discovery Research, Temple University, School of Pharmacy, 3307 N. Broad Street, Philadelphia, Pennsylvania 19140, United States.
  • Rico M; Department of Pharmaceutical Chemistry, Tanta University, Tanta 31527, Egypt.
  • Gordon J; Division of Pharmaceutical Sciences, Arnold and Marie Schwartz College of Pharmacy and Health Sciences, Long Island University, Brooklyn, New York 11201, United States.
  • Mateo G; Moulder Center for Drug Discovery Research, Temple University, School of Pharmacy, 3307 N. Broad Street, Philadelphia, Pennsylvania 19140, United States.
  • Omar AM; Moulder Center for Drug Discovery Research, Temple University, School of Pharmacy, 3307 N. Broad Street, Philadelphia, Pennsylvania 19140, United States.
  • Abou-Gharbia M; Moulder Center for Drug Discovery Research, Temple University, School of Pharmacy, 3307 N. Broad Street, Philadelphia, Pennsylvania 19140, United States.
  • Childers WE; Moulder Center for Drug Discovery Research, Temple University, School of Pharmacy, 3307 N. Broad Street, Philadelphia, Pennsylvania 19140, United States.
ACS Med Chem Lett ; 11(11): 2156-2164, 2020 Nov 12.
Article em En | MEDLINE | ID: mdl-33214824
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Idioma: En Revista: ACS Med Chem Lett Ano de publicação: 2020 Tipo de documento: Article
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Idioma: En Revista: ACS Med Chem Lett Ano de publicação: 2020 Tipo de documento: Article