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An adenoviral vector encoded with the GPx-1 gene attenuates memory impairments induced by ß-amyloid (1-42) in GPx-1 KO mice via activation of M1 mAChR-mediated signalling.
Shin, Eun-Joo; Lee, Sung Hoon; Sharma, Naveen; Nguyen, Bao Trong; Chung, Yoon Hee; Kang, Sang Won; Nah, Seung-Yeol; Lee, Yu Jeung; Nabeshima, Toshitaka; Jeong, Ji Hoon; Kim, Hyoung-Chun.
Afiliação
  • Shin EJ; Neuropsychopharmacology and Toxicology Program, College of Pharmacy, Kangwon National University, Chunchon, Republic of Korea.
  • Lee SH; Department of Pharmacology, College of Pharmacy, Chung-Ang University, Seoul, Republic of Korea.
  • Sharma N; Neuropsychopharmacology and Toxicology Program, College of Pharmacy, Kangwon National University, Chunchon, Republic of Korea.
  • Nguyen BT; Neuropsychopharmacology and Toxicology Program, College of Pharmacy, Kangwon National University, Chunchon, Republic of Korea.
  • Chung YH; Department of Anatomy, College of Medicine, Chung-Ang University, Seoul, Korea.
  • Kang SW; Department of Life Science, College of Natural science, Ewha Womans University, Seoul, Republic of Korea.
  • Nah SY; Ginsentology Research Laboratory and Department of Physiology, College of Veterinary Medicine and Bio/Molecular Informatics Center, Konkuk University, Seoul, Republic of Korea.
  • Lee YJ; Clinical Pharmacy, College of Pharmacy, Kangwon National University, Chunchon, Republic of Korea.
  • Nabeshima T; Advanced Diagnostic System Research Laboratory, Fujita Health University Graduate School of Health Sciences, Aichi, Japan.
  • Jeong JH; Department of Global Innovative Drugs, Graduate School of Chung-Ang University, College of Medicine, Chung-Ang University, Seoul, Republic of Korea.
  • Kim HC; Neuropsychopharmacology and Toxicology Program, College of Pharmacy, Kangwon National University, Chunchon, Republic of Korea.
Free Radic Res ; 55(1): 11-25, 2021 Jan.
Article em En | MEDLINE | ID: mdl-33222572

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Fragmentos de Peptídeos / Peptídeos beta-Amiloides / Receptor Muscarínico M1 / Glutationa Peroxidase / Transtornos da Memória Tipo de estudo: Prognostic_studies Limite: Animals Idioma: En Revista: Free Radic Res Ano de publicação: 2021 Tipo de documento: Article

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Fragmentos de Peptídeos / Peptídeos beta-Amiloides / Receptor Muscarínico M1 / Glutationa Peroxidase / Transtornos da Memória Tipo de estudo: Prognostic_studies Limite: Animals Idioma: En Revista: Free Radic Res Ano de publicação: 2021 Tipo de documento: Article