A Biomimetic DNA-Based Membrane Gate for Protein-Controlled Transport of Cytotoxic Drugs.

Lanphere, Conor; Arnott, Patrick M; Jones, Sioned Fôn; Korlova, Katarina; Howorka, Stefan

Lanphere, Conor; Arnott, Patrick M; Jones, Sioned Fôn; Korlova, Katarina; Howorka, Stefan.

Afiliação

Lanphere C; Department of Chemistry, Institute of Structural and Molecular Biology, University College London, London, WC1H 0AJ, UK.
Arnott PM; Department of Biochemical Engineering, University College London, London, WC1E 7JE, UK.
Jones SF; Department of Chemistry, Institute of Structural and Molecular Biology, University College London, London, WC1H 0AJ, UK.
Korlova K; Department of Chemistry, King's College London, London, SE1 1DB, UK.
Howorka S; Department of Chemistry, Institute of Structural and Molecular Biology, University College London, London, WC1H 0AJ, UK.

Angew Chem Int Ed Engl ; 60(4): 1903-1908, 2021 01 25.

Article em En | MEDLINE | ID: mdl-33231913

Assuntos

Antineoplásicos/metabolismo; Biomimética; DNA/química; Bicamadas Lipídicas/metabolismo; Proteínas/metabolismo; Transporte Biológico

Palavras-chave

DNA structures; aptamers; biosensors; membrane; nanopores

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: DNA / Proteínas / Biomimética / Bicamadas Lipídicas / Antineoplásicos Idioma: En Revista: Angew Chem Int Ed Engl Ano de publicação: 2021 Tipo de documento: Article

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