Cross-sectional analysis of plasma and CSF metabolomic markers in Huntington's disease for participants of varying functional disability: a pilot study.

McGarry, Andrew; Gaughan, John; Hackmyer, Cory; Lovett, Jacqueline; Khadeer, Mohammed; Shaikh, Hamza; Pradhan, Basant; Ferraro, Thomas N; Wainer, Irving W; Moaddel, Ruin

McGarry, Andrew; Gaughan, John; Hackmyer, Cory; Lovett, Jacqueline; Khadeer, Mohammed; Shaikh, Hamza; Pradhan, Basant; Ferraro, Thomas N; Wainer, Irving W; Moaddel, Ruin.

Afiliação

McGarry A; Department of Neurology, Cooper University Hospital and Cooper Medical School of Rowan University, Camden, NJ, USA. McGarry-Andrew@CooperHealth.edu.
Gaughan J; Department of Neurology, Cooper University Hospital and Cooper Medical School of Rowan University, Camden, NJ, USA.
Hackmyer C; Department of Neurology, Cooper University Hospital and Cooper Medical School of Rowan University, Camden, NJ, USA.
Lovett J; Biomedical Research Center, National Institute On Aging, National Institutes of Health, Baltimore, MD, 21224, USA.
Khadeer M; Biomedical Research Center, National Institute On Aging, National Institutes of Health, Baltimore, MD, 21224, USA.
Shaikh H; Department of Neurology, Cooper University Hospital and Cooper Medical School of Rowan University, Camden, NJ, USA.
Pradhan B; Department of Neurology, Cooper University Hospital and Cooper Medical School of Rowan University, Camden, NJ, USA.
Ferraro TN; Department of Biomedical Sciences, Cooper Medical School of Rowan University, Camden, NJ, USA.
Wainer IW; Department of Neurology, Cooper University Hospital and Cooper Medical School of Rowan University, Camden, NJ, USA.
Moaddel R; Biomedical Research Center, National Institute On Aging, National Institutes of Health, Baltimore, MD, 21224, USA. moaddelru@grc.nia.nih.gov.

Sci Rep ; 10(1): 20490, 2020 11 24.

Article em En | MEDLINE | ID: mdl-33235276

Assuntos

Biomarcadores/sangue; Biomarcadores/líquido cefalorraquidiano; Avaliação da Deficiência; Doença de Huntington/sangue; Doença de Huntington/líquido cefalorraquidiano; Metabolômica; Adulto; Arginina/sangue; Arginina/líquido cefalorraquidiano; Creatina/sangue; Creatina/líquido cefalorraquidiano; Estudos Transversais; Feminino; Glicina/sangue; Glicina/líquido cefalorraquidiano; Humanos; Doença de Huntington/metabolismo; Masculino; Pessoa de Meia-Idade; Projetos Piloto; Resultado do Tratamento; Adulto Jovem

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Biomarcadores / Doença de Huntington / Avaliação da Deficiência / Metabolômica Tipo de estudo: Observational_studies / Prevalence_studies / Risk_factors_studies Limite: Adult / Female / Humans / Male / Middle aged Idioma: En Revista: Sci Rep Ano de publicação: 2020 Tipo de documento: Article

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